SCHEMBL1403608

SCHEMBL1403608

CCS(=O)(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
HSD17B10 Q99714 1/20 0.61
PSIP1 O75475 2/20 0.58
CA2 P00918 6/20 0.58
CA12 O43570 5/20 0.58
CA9 Q16790 5/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
RAB9A P51151 1/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
SLC22A8 Q8TCC7 1/20 0.58
ABCC2 Q92887 1/20 0.58
SLC22A12 Q96S37 1/20 0.58
UGT1A7 Q9HAW7 1/20 0.58
SLC22A11 Q9NSA0 1/20 0.58
CA1 P00915 4/20 0.57
CA14 Q9ULX7 2/20 0.57
CA3 P07451 1/20 0.57
CA6 P23280 1/20 0.57
CYP2C19 P33261 1/20 0.57
CA5A P35218 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1018690 0.86 CA12 (0.57) TSHRHSD17B10CA2CA12CA9
SCHEMBL28353018 0.82 RORC (0.66) TSHRCA2CA1ALDH1A1KMT2A
SCHEMBL27317432 0.81 THRA (0.61) TSHRHSD17B10CA2CA12CA9
SCHEMBL10335262 0.81 KDM4E (0.50) TSHRHSD17B10PSIP1CA2CA12
SCHEMBL10803103 0.81 MMP2 (0.63) TSHRHSD17B10CA2CA12CA9
SCHEMBL4639123 0.81 CA2 (0.61) TSHRHSD17B10PSIP1CA2CA12
SCHEMBL10451127 0.81 PSIP1 (0.50) TSHRHSD17B10PSIP1CA2CA12
SCHEMBL9067141 0.81 PSIP1 (0.50) TSHRHSD17B10PSIP1CA2CA12
SCHEMBL13861088 0.81 MAPT (0.52) PSIP1SMN1; SMN2ALDH1A1GAAKMT2A
SCHEMBL10455034 0.81 PSIP1 (0.74) PSIP1CA2SMN1; SMN2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114512671-A Cross-linking type adhesive, preparation method and application thereof 江苏中兴派能电池有限公司 2022-05-17 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
CN-111108109-A Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors 利奥制药有限公司 2020-05-05 CN claimed
CN-110099905-A SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 利奥制药有限公司 2019-08-06 CN claimed
CN-110088108-A SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 利奥制药有限公司 2019-08-02 CN claimed
CN-114206335-B KCNT1 inhibitors and methods of use 普拉克西斯精密药物股份有限公司 2025-03-11 CN disclosed
EP-4446314-A2 KCNT1 INHIBITORS AND METHODS OF USE Praxis Precision Medicines, Inc. (US) 2024-10-16 EP disclosed
EP-3962479-B1 KCNT1 INHIBITORS AND METHODS OF USE PRAXIS PREC MEDICINES INC (US) 2024-07-24 EP disclosed
EP-3458447-B1 PIPERAZINYL METHANONE NAAA INHIBITORS UNIV CALIFORNIA (US) 2023-11-29 EP disclosed
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 US disclosed
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 US disclosed
CN-109476616-B Piperazinyl methanone NAAA inhibitors 加利福尼亚大学董事会 2023-10-13 CN disclosed
EP-0792345-A1 BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP disclosed
EP-0792344-A1 BLEACHING DETERGENT COMPOSITIONS COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP disclosed
EP-0792343-A1 USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1997-09-03 EP disclosed
US-5635104-A Bleaching solutions and method utilizing selected bleach activators effective at low perhydroxyl concentrations THE PROCTER & GAMBLE COMPANY (US) 1997-06-03 US disclosed
WO-1996016155-A1 BLEACHING COMPOSITIONS AND BLEACH-ADDITIVES COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO disclosed
WO-1996016156-A1 USE OF BLEACH ACTIVATORS FOR LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO disclosed
WO-1996016157-A1 BLEACHING DETERGENT COMPOSITIONS COMPRISING BLEACH ACTIVATORS EFFECTIVE AT LOW PERHYDROXYL CONCENTRATIONS THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO disclosed
US-3975288-A High temperature non-crystallizing cholesteric liquid crystal compositions RPR, INC. (US) 1976-08-17 US disclosed