SCHEMBL140436

SCHEMBL140436

Cc1ccc(S(=O)(=O)Oc2ccc3nc(C#N)sc3c2)c([N+](=O)[O-])c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.43
CA2 P00918 2/20 0.41
ALPL P05186 1/20 0.41
LMNA P02545 3/20 0.38
NPC1 O15118 2/20 0.38
MEN1 O00255 7/20 0.38
KMT2A Q03164 7/20 0.38
RAB9A P51151 1/20 0.38
NFKBIA P25963 2/20 0.38
RELA Q04206 2/20 0.38
MAPT P10636 4/20 0.37
AGTR1 P30556 1/20 0.37
OPRK1 P41145 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SCD O00767 1/20 0.37
ALDH1A1 P00352 3/20 0.36
GAA P10253 1/20 0.36
RORC P51449 1/20 0.36
CA1 P00915 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138994 0.92 PTPN1 (0.43) PTPN1CA2ALPLLMNANPC1
SCHEMBL139851 0.87 ALPL (0.49) PTPN1CA2ALPLNPC1MEN1
SCHEMBL137699 0.84 HTT (0.45) PTPN1CA2ALPLNPC1MEN1
SCHEMBL12312893 0.83 CA2 (0.44) PTPN1CA2ALPLLMNANPC1
SCHEMBL137701 0.81 NQO1 (0.46) ALPLMEN1KMT2ANFKBIARELA
SCHEMBL183510 0.80 CA2 (0.41) CA2LMNANPC1KMT2AMAPT
SCHEMBL19393227 0.78 CA2 (0.38) PTPN1CA2LMNANPC1MEN1
SCHEMBL17856924 0.77 PTPN1 (0.38) PTPN1CA2LMNAMEN1KMT2A
SCHEMBL138997 0.77 PTPN1 (0.38) PTPN1CA2LMNAMEN1KMT2A
SCHEMBL17856888 0.74 GPR35 (0.43) PTPN1CA2LMNANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889849-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2021-01-12 US disclosed
US-20180030503-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-02-01 US disclosed
US-20180030503-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-02-01 US disclosed
US-9816127-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2017-11-14 US disclosed
US-9816127-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2017-11-14 US disclosed
US-9816127-B2 Oxidized glutathione assay PROMEGA CORPORATION (US) 2017-11-14 US disclosed
EP-2611929-B1 OXIDIZED GLUTATHIONE ASSAY PROMEGA CORP (US) 2016-01-13 EP disclosed
EP-2611929-B1 OXIDIZED GLUTATHIONE ASSAY PROMEGA CORP (US) 2016-01-13 EP disclosed
EP-2611929-A1 OXIDIZED GLUTATHIONE ASSAY Promega Corporation (US) 2013-07-10 EP disclosed
US-20120058501-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2012-03-08 US disclosed
US-20120058501-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2012-03-08 US disclosed
US-20120058501-A1 OXIDIZED GLUTATHIONE ASSAY JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2012-03-08 US disclosed
WO-2012030960-A1 OXIDIZED GLUTATHIONE ASSAY PROMEGA CORPORATION (US) 2012-03-08 WO disclosed
WO-2012030960-A1 OXIDIZED GLUTATHIONE ASSAY PROMEGA CORPORATION (US) 2012-03-08 WO disclosed