Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12652646 | 0.86 | CA2 (0.39) | CA2NPC1CA1MAPTALDH1A1 | |
| SCHEMBL138994 | 0.82 | PTPN1 (0.43) | CA2LMNANPC1CA1KDM4E | |
| SCHEMBL140436 | 0.80 | PTPN1 (0.43) | CA2LMNANPC1CA1KDM4E | |
| SCHEMBL183225 | 0.76 | GPR35 (0.35) | CA2LMNANPC1CA1KDM4E | |
| SCHEMBL137699 | 0.74 | HTT (0.45) | CA2NPC1MAPTALDH1A1ACP1 | |
| SCHEMBL12872411 | 0.73 | RAB9A (0.56) | LMNANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL139851 | 0.72 | ALPL (0.49) | CA2NPC1CA1MAPTALDH1A1 | |
| SCHEMBL26691684 | 0.72 | CA2 (0.63) | CA2LMNANPC1CA1KDM4E | |
| SCHEMBL12312893 | 0.71 | CA2 (0.44) | CA2LMNANPC1CA1MAPT | |
| SCHEMBL906609 | 0.69 | CYP1A2 (0.59) | LMNANPC1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058501-A1 | OXIDIZED GLUTATHIONE ASSAY | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2012-03-08 | — | — | US | disclosed |