Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049932 | 0.77 | NR1H4 (0.61) | EPHX2NR1H4CFDERN1ALDH1A1 | |
| SCHEMBL10053522 | 0.72 | ROCK2 (0.75) | — | |
| SCHEMBL14049934 | 0.70 | PPARG (0.55) | NR1H4HDAC3HDAC1ALDH1A1NPC1 | |
| SCHEMBL4445945 | 0.70 | XDH (0.44) | EPHX2NR1H4XDHHDAC3HDAC1 | |
| SCHEMBL4445961 | 0.70 | XDH (0.44) | EPHX2NR1H4XDHHDAC3HDAC1 | |
| SCHEMBL3043353 | 0.70 | FAAH (0.51) | EPHX2NR1H4XDHHDAC3HDAC1 | |
| SCHEMBL24821278 | 0.69 | ERN1 (0.49) | NR1H4ERN1ALDH1A1 | |
| SCHEMBL1249264 | 0.69 | HIF1A (0.58) | EPHX2NR1H4XDHMAPTCSNK2A1 | |
| SCHEMBL2664262 | 0.68 | MEP1B (0.60) | NR1H4 | |
| SCHEMBL24690112 | 0.68 | CFD (0.46) | EPHX2NR1H4XDHHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |