Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | RARB | P10826 | 11/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477961 | 0.90 | RAB9A (0.40) | HSD17B1RARBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16477987 | 0.89 | PTPN11 (0.35) | PTPN11RARBMAPTMEN1ALDH1A1 | |
| SCHEMBL16477991 | 0.87 | MGLL (0.34) | PTPN11RARBMAPT | |
| SCHEMBL16477966 | 0.86 | PTPN11 (0.36) | PTPN11RARBMAPTMEN1ALDH1A1 | |
| SCHEMBL16477977 | 0.84 | THRA (0.36) | HSD17B1RARBMAPTMEN1ALDH1A1 | |
| SCHEMBL16477968 | 0.83 | PTPN11 (0.44) | PTPN11ALDH1A1 | |
| SCHEMBL18256537 | 0.80 | RARB (0.54) | PTPN11RARBMAPTMEN1ALDH1A1 | |
| SCHEMBL27837668 | 0.79 | MAPT (0.44) | HSD17B1RARBMAPTALDH1A1 | |
| SCHEMBL16477992 | 0.78 | CNR2 (0.43) | ALDH1A1 | |
| SCHEMBL16477975 | 0.78 | PPARG (0.33) | PTPN11MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714659-B1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE INC (CA) | 2017-07-05 | — | — | EP | disclosed |
| US-9382259-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-07-05 | — | — | US | disclosed |
| US-9382259-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-07-05 | — | — | US | disclosed |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-01-21 | — | — | US | disclosed |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-01-21 | — | — | US | disclosed |
| US-9127017-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2015-09-08 | — | — | US | disclosed |
| US-9127017-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20140200350-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE, INC. (CA) | 2014-07-17 | — | — | US | disclosed |
| WO-2012159213-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE, INC. (CA) | 2012-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200350-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | PPOX, SCO2, LPO | HSD17B1 1063/4885PTPN11 3309/4885RARB 399/4885 |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | SCO2, PPOX, SQOR | HSD17B1 1099/4885PTPN11 3497/4885RARB 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.