Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477965 | 0.93 | CNR2 (0.39) | CNR2PDK2L3MBTL1ATMTDP1 | |
| SCHEMBL16477969 | 0.87 | MMP2 (0.43) | CNR2ALDH1A1MMP2MMP9MMP8 | |
| SCHEMBL16477967 | 0.86 | CNR2 (0.39) | CNR2ALDH1A1 | |
| SCHEMBL16477961 | 0.85 | RAB9A (0.40) | PDK2ALDH1A1HPGD | |
| SCHEMBL17084318 | 0.84 | PDK2 (0.41) | CNR2PDK2L3MBTL1ATMTDP1 | |
| SCHEMBL16477970 | 0.83 | PDK2 (0.46) | CNR2PDK2ALDH1A1HPGD | |
| SCHEMBL17056201 | 0.80 | PDK2 (0.41) | CNR2PDK2ALDH1A1LTB4RCES2 | |
| SCHEMBL16477977 | 0.80 | THRA (0.36) | PDK2ALDH1A1HPGD | |
| SCHEMBL15159198 | 0.78 | PDK2 (0.42) | CNR2PDK2MMP2MMP9MMP8 | |
| SCHEMBL14060977 | 0.78 | HSD17B1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382259-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-07-05 | — | — | US | disclosed |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-01-21 | — | — | US | disclosed |
| US-9127017-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20140200350-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE, INC. (CA) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200350-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | PPOX, SCO2, LPO | CNR2 1259/4885PDK2 1248/4885L3MBTL1 1864/4885 |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | SCO2, PPOX, SQOR | CNR2 1195/4885PDK2 1309/4885L3MBTL1 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.