Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 3/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375632 | 1.00 | KDM4E (0.40) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL2599669 | 0.97 | KDM4E (0.39) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL29501170 | 0.96 | ALDH1A1 (0.41) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL2412684 | 0.96 | ALDH1A1 (0.41) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL4784200 | 0.95 | NCF1 (0.42) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL8506443 | 0.94 | NPSR1 (0.40) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL12618090 | 0.91 | NCF1 (0.43) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL675528 | 0.91 | MAPT (0.36) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL7480012 | 0.90 | ALDH1A1 (0.39) | KDM4ELMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL2599684 | 0.89 | BCHE (0.44) | KDM4ELMNAMAPTNPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1410786-B1 | Cosmetic composition comprising at least two dyes whereof at least one is photochromic | OREAL (FR) | 2008-01-02 | — | — | EP | claimed |
| EP-1410784-B1 | Cosmetic composition comprising an oil phase and a naphthopyran dye and method | OREAL (FR) | 2007-02-07 | — | — | EP | claimed |
| EP-1410785-B1 | Make-up product, combining two compositions, comprising a photochromic dye and a goniochromatic agent, respectively | OREAL (FR) | 2007-01-03 | — | — | EP | claimed |
| US-20050276767-A1 | Composition containing an oily phase and a naphthopyran dye, cosmetic treatment processes | L'OREAL (FR) | 2005-12-15 | — | — | US | claimed |
| US-20040228817-A1 | Makeup combining at least one photochromic dye and at least one goniochromatic agent | L'OREAL (FR) | 2004-11-18 | — | — | US | claimed |
| US-20040228818-A1 | Cosmetic composition combining at least two dyes including at least one photochromic dye | L'OREAL (FR) | 2004-11-18 | — | — | US | claimed |
| EP-1410784-A1 | Cosmetic composition comprising an oil phase and a naphthopyran dye and method | L'OREAL (FR) | 2004-04-21 | — | — | EP | claimed |
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | claimed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | claimed |
| WO-1999031081-A1 | PH SENSITIVE PHOTOCHROMIC DYES | JAMES ROBINSON LIMITED (GB) | 1999-06-24 | — | — | WO | claimed |
| US-20250345255-A1 | COMPOSITIONS FOR IMPROVING NAIL HEALTH | L'ORÉAL (FR) | 2025-11-13 | — | — | US | disclosed |
| EP-3989772-B1 | METHOD FOR SHAPING AN APPLICATOR FOR APPLYING A COSMETIC COMPOSITION | OREAL (FR) | 2024-04-10 | — | — | EP | disclosed |
| CN-114615912-B | System for picking up and applying a cosmetic composition | 欧莱雅 | 2024-03-08 | — | — | CN | disclosed |
| EP-4051053-B1 | SYSTEM FOR TAKING UP AND APPLYING A COSMETIC COMPOSITION | OREAL (FR) | 2023-11-08 | — | — | EP | disclosed |
| EP-3086853-B1 | MAKEUP DEVICE COMPRISING A PLURALITY OF COSMETIC DYES | OREAL (FR) | 2023-08-09 | — | — | EP | disclosed |
| US-6306316-B1 | Photochromic plastic object | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-10-23 | — | — | US | disclosed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |
| EP-1099743-A1 | Photochromic plastic article | Optische Werke G. Rodenstock (DE) | 2001-05-16 | — | — | EP | disclosed |
| EP-1018038-A1 | PHOTOCHROMIC PLASTIC OBJECT | Optische Werke G. Rodenstock (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-2000005602-A1 | PHOTOCHROMIC PLASTIC OBJECT | OPTISCHE WERKE G. RODENSTOCK (DE) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040228817-A1 | Makeup combining at least one photochromic dye and at least one goniochromatic agent | GYPA, TYR, GLA | KDM4E 4265/4885LMNA 2308/4885MAPT 3990/4885 |
| US-20050276767-A1 | Composition containing an oily phase and a naphthopyran dye, cosmetic treatment processes | CUTA, TYR, TPSD1 | KDM4E 4667/4885LMNA 942/4885MAPT 3880/4885 |
| US-20040228818-A1 | Cosmetic composition combining at least two dyes including at least one photochromic dye | CUTA, TYR, LAGE3 | KDM4E 3484/4885LMNA 423/4885MAPT 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.