SCHEMBL141000

SCHEMBL141000

CCc1nccn1CCCN

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.51
ALDH1A1 P00352 2/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
ALPG P10696 2/20 0.39
PLAA Q9Y263 1/20 0.39
ALPL P05186 1/20 0.38
KCNH2 Q12809 4/20 0.38
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
ARG1 P05089 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11091402 0.98 TLR8 (0.53) TLR8ALDH1A1POLBKMT2AALPG
SCHEMBL27627065 0.95 TLR8 (0.54) TLR8ALDH1A1POLBKMT2AALPG
SCHEMBL2792249 0.89 TLR8 (0.46) TLR8ALDH1A1POLBKMT2AALPG
SCHEMBL22356840 0.86 TLR8 (0.49) TLR8ALDH1A1POLBKMT2AKCNH2
SCHEMBL329466 0.85 ALDH1A1 (0.63) TLR8ALDH1A1POLBKMT2AALPG
SCHEMBL27627062 0.84 TLR8 (0.51) TLR8ALDH1A1POLBKMT2AKCNH2
Iodide SCHEMBL4267902 0.83 ALDH1A1 (0.61) TLR8ALDH1A1POLBKMT2AALPG
Hydrochloric Acid SCHEMBL28286020 0.83 ALDH1A1 (0.61) TLR8ALDH1A1POLBKMT2AALPG
SCHEMBL4227901 0.83 TLR8 (0.68) TLR8ALDH1A1POLBKMT2AALPG
SCHEMBL10530747 0.82 TLR8 (0.53) TLR8ALDH1A1POLBKMT2AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11471821-B2 Process for biogas upgradation INDIAN OIL CORPORATION LIMITED (IN) 2022-10-18 US claimed
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN claimed
EP-1971600-B1 ISOXAZOLE DERIVATIVES AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2013-08-21 EP claimed
US-7479527-B2 Polyepoxide and reaction product of aminoalkylimidazole, polyamine, urea and diepoxide as curing component FUJI KASEI KOGYO CO., LTD. (JP) 2009-01-20 US claimed
EP-4747320-A1 THERMAL-AND UV-CURABLE (METH) ACRYLATE COMPOSITION Henkel AG & Co. KGaA (DE) 2026-05-27 EP disclosed
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION HENKEL AG & CO KGAA (DE) 2026-05-21 US disclosed
US-12570797-B2 Acid functional compound BYK-CHEMIE GMBH (DE) 2026-03-10 US disclosed
EP-4526365-A1 ACRYLATE-EPOXY RESIN COMPOSITIONS Lyondellbasell Composites LLC (US) 2025-03-26 EP disclosed
WO-2025015542-A1 THERMAL-AND UV-CURABLE (METH) ACRYLATE COMPOSITION HENKEL AG & CO. KGAA (DE) 2025-01-23 WO disclosed
EP-3665209-B1 AN AMINE FUNCTIONAL COMPOUND BYK CHEMIE GMBH (DE) 2024-11-20 EP disclosed
US-20240327582-A1 RAPID CURING EPOXY-RESIN COMPOSITION FOR FIBER-MATRIX SEMIFINISHED PRODUCTS POLYNT COMPOSITES NORWAY AS (NO) 2024-10-03 US disclosed
US-20230416522-A1 ACRYLATE-EPOXY RESIN COMPOSITIONS LYONDELLBASELL COMPOSITES LLC (US) 2023-12-28 US disclosed
US-4576957-A HYPOTENSIVE AMERICAN CYANAMID COMPANY (US) 1986-03-18 US disclosed
US-4568687-A THROMBOXANE SYNTHETASE TNZYME INHIBITORS; HYPOTENSIVE AGENTS, CARDIOTONIC AGENTS AMERICAN CYANAMID COMPANY (US) 1986-02-04 US disclosed
EP-0091641-B1 N-SUBSTITUTED IMIDAZOLE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE BASF Aktiengesellschaft (DE) 1986-01-02 EP disclosed
US-4555519-A Thromboxane synthetase enzyme inhibiting N-[(1H-imidazol-1-yl) and (1H-1,2,4-triazol-1-yl)alkyl]pyridinecarboxamides AMERICAN CYANAMID COMPANY (US) 1985-11-26 US disclosed
US-4514413-A ANTACIDS BASF AKTIENGESELLSCHAFT (DE) 1985-04-30 US disclosed
EP-0117462-A2 N-(2-4-(1H-imidazol-1-yl)alkyl)arylamides AMERICAN CYANAMID COMPANY (US) 1984-09-05 EP disclosed
EP-0091641-A1 N-substituted imidazole derivatives, their preparation, pharmaceutical compositions containing them and their use BASF Aktiengesellschaft (DE) 1983-10-19 EP disclosed
US-3949076-A GASTRIC ACID SECRETION INHIBITION SMITHKLINE CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION MAT1A, MAT2B, MAT2A TLR8 2733/4885ALDH1A1 139/4885POLB 1381/4885
US-12570797-B2 Acid functional compound ELOVL1, ELOVL6, ELOVL5 TLR8 2149/4885ALDH1A1 306/4885POLB 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.