Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720876 | 0.90 | CYP11B1 (0.33) | LRRK2GRM7NTRK1ALPLALPI | |
| SCHEMBL4764976 | 0.89 | CNR1 (0.34) | LRRK2GRM7NTRK1ALPLALPI | |
| SCHEMBL4719266 | 0.89 | LRRK2 (0.33) | LRRK2GRM7NTRK1ALPLALPI | |
| SCHEMBL4722103 | 0.88 | L3MBTL1 (0.35) | GRM7ALPLALPI | |
| SCHEMBL4724987 | 0.86 | F10 (0.40) | LRRK2F10 | |
| SCHEMBL4724951 | 0.84 | NTRK1 (0.32) | LRRK2GRM7NTRK1 | |
| SCHEMBL4721216 | 0.84 | F10 (0.32) | LRRK2ALPLALPIF10 | |
| SCHEMBL4718926 | 0.82 | F10 (0.32) | GRM7F10 | |
| SCHEMBL4724753 | 0.82 | BRAF (0.33) | NTRK1F10 | |
| SCHEMBL4718899 | 0.81 | CYP11B2 (0.44) | GRM7CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |