Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765008 | 0.95 | NTRK1 (0.31) | NTRK1 | |
| SCHEMBL4721949 | 0.89 | NTRK1 (0.33) | NTRK1 | |
| SCHEMBL4719906 | 0.87 | BRD4 (0.34) | GRM7 | |
| SCHEMBL4720876 | 0.85 | CYP11B1 (0.33) | NTRK1GRM7MAPTLRRK2 | |
| SCHEMBL4722103 | 0.84 | L3MBTL1 (0.35) | GRM7MEN1GAAMAPTKMT2A | |
| SCHEMBL4719266 | 0.84 | LRRK2 (0.33) | NTRK1GRM7LRRK2 | |
| SCHEMBL14101738 | 0.84 | LRRK2 (0.33) | NTRK1GRM7LRRK2 | |
| SCHEMBL4764976 | 0.84 | CNR1 (0.34) | NTRK1GRM7LRRK2 | |
| SCHEMBL4723419 | 0.84 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL4723635 | 0.83 | PDE4A (0.38) | GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |