Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231821 | 0.91 | ALDH1A1 (0.35) | CES2ALDH1A1TSHR | |
| SCHEMBL12678049 | 0.84 | ALDH1A1 (0.45) | CES2ALDH1A1TSHR | |
| SCHEMBL3891542 | 0.81 | ALDH1A1 (0.38) | CES2ALDH1A1TSHR | |
| SCHEMBL18660230 | 0.80 | ALDH1A1 (0.47) | CES2ACHEPAOXALDH1A1TSHR | |
| SCHEMBL3901977 | 0.79 | ALDH1A1 (0.47) | CES2ALDH1A1TSHR | |
| SCHEMBL1921248 | 0.78 | ALDH1A1 (0.50) | CES2ACHEPAOXALDH1A1TSHR | |
| SCHEMBL704685 | 0.76 | KDM4E (0.36) | PAOXALDH1A1TSHR | |
| SCHEMBL703686 | 0.76 | KDM4E (0.36) | PAOXALDH1A1TSHR | |
| SCHEMBL143448 | 0.75 | CES2 (0.35) | CES2 | |
| SCHEMBL3899362 | 0.75 | TSHR (0.39) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161464-A1 | Crosslinked polymeric dielectric materials and methods of manufacturing and use thereof | USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA | 2008-07-03 | — | — | US | disclosed |