Adenosine Phosphate

Adenosine Phosphate

SCHEMBL1416760

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])O)[C@@H](O)[C@H]1O.[Na+]

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Adenosine Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 known ✓ P47900 9/20 0.83
P2RY2 known ✓ P41231 3/20 0.83
ADORA1 known ✓ P30542 1/20 0.83
PDE4D known ✓ Q08499 1/20 0.83
PDE3A known ✓ Q14432 1/20 0.83
P2RY11 Q96G91 3/20 0.83
SRC P12931 2/20 0.83
SMN1; SMN2 Q16637 2/20 0.83
TRPM2 O94759 2/20 0.83
TAS1R3 Q7RTX0 2/20 0.83
TAS1R1 Q7RTX1 2/20 0.83
DNPH1 O43598 1/20 0.83
PRKAB2 O43741 1/20 0.83
LDHA P00338 1/20 0.83
ADRB2 P07550 1/20 0.83
FBP1 P09467 1/20 0.83
PRKAG1 P54619 1/20 0.83
PRKAA2 P54646 1/20 0.83
KCNH2 Q12809 1/20 0.83
PRKAA1 Q13131 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Phosphate SCHEMBL29574456 1.00 P2RY1 (0.83) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL29558795 0.98 P2RY1 (0.83) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL8425208 0.97 P2RY1 (0.89) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL28252058 0.97 P2RY1 (0.81) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL29364783 0.94 P2RY1 (0.83) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL353218 0.94 P2RY1 (0.83) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL1356934 0.94 P2RY1 (0.83) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL145417 0.94 P2RY1 (0.83) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL23093554 0.93 P2RY1 (0.81) P2RY1P2RY2P2RY11SRCSMN1; SMN2
Adenosine Phosphate SCHEMBL9068130 0.93 P2RY1 (0.81) P2RY1P2RY2P2RY11SRCSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467715-A Process for simultaneously preparing D-glutamic acid and L-glutathione by multi-step enzyme method 珠海瑞德林生物有限公司 2024-01-30 CN claimed
CN-112707966-A Protein and hierarchical pore metal-organic framework compound and preparation method and application thereof 华南理工大学 2021-04-27 CN claimed
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof FERRER INTERNACIONAL, S.A. (ES) 2026-01-27 US disclosed
CN-116410938-B Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2024-03-12 CN disclosed
CN-117467715-A Process for simultaneously preparing D-glutamic acid and L-glutathione by multi-step enzyme method 珠海瑞德林生物有限公司 2024-01-30 CN disclosed
CN-113784706-B Multi-layered pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and B vitamins, their preparation and use 菲尔若国际公司 2024-01-05 CN disclosed
EP-3335693-B1 COMPOSITION FOR EXTERNAL USE OTSUKA PHARMA CO LTD (JP) 2023-09-13 EP disclosed
CN-116410938-A Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2023-07-11 CN disclosed
CN-116376853-A Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2023-07-04 CN disclosed
CN-115820578-A Mutant composition, fusion enzyme and preparation method of collagen tripeptide 深圳瑞德林生物技术有限公司 2023-03-21 CN disclosed
US-20220160744-A1 MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF FERRER INTERNACIONAL, S.A. (ES) 2022-05-26 US disclosed
US-20050220827-A1 Chloasma amelioration composition and dullness amelioration composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 US disclosed
US-20050222076-A1 Composition for cell proliferation OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 US disclosed
US-6946436-B2 O/W emulsion composition and method of preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-09-20 US disclosed
EP-1512405-A1 CHLOASMA AMELIORATION COMPOSITION AND DULLNESS AMELIORATION COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-03-09 EP disclosed
EP-1498101-A1 COMPOSITION FOR CELL PROLIFERATION Otsuka Pharmaceutical Company, Limited (JP) 2005-01-19 EP disclosed
US-20040116373-A1 Sugar intake promoters OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-06-17 US disclosed
US-20040029761-A1 O/W emulsion composition and method of preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-02-12 US disclosed
EP-1378224-A1 SUGAR INTAKE PROMOTERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-01-07 EP disclosed
EP-1342462-A1 O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof P2RY10, TYMP, P2RY12 P2RY1 14/4885P2RY2 42/4885ADORA1 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.