SCHEMBL14168751

SCHEMBL14168751

CC(C)CC(C)(C)c1ccc(O)c(-n2n3c4ccccc4n23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 3/20 0.36
▸ RORC P51449 1/20 0.33
▸ ESR1 P03372 1/20 0.32
▸ ESR2 Q92731 1/20 0.32
▸ CYP2D6 P10635 1/20 0.31
▸ CACNA1B Q00975 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ NFKB1 P19838 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ BLM P54132 1/20 0.30
▸ PMP22 Q01453 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ KCNMA1 Q12791 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9002356 0.83 CYP3A4 (0.45) HSP90AA1ESR1ESR2CYP2D6MEN1
SCHEMBL9002493 0.81 ALDH1A1 (0.48) HSP90AA1ESR1ESR2CYP2D6MEN1
SCHEMBL13927492 0.79 CNR2 (0.51) —
SCHEMBL13652819 0.77 ESR1 (0.47) HSP90AA1RORCESR1ESR2CYP2D6
SCHEMBL18574379 0.74 ALOX15 (0.55) HSP90AA1RORCESR1ESR2CYP2D6
SCHEMBL9002510 0.70 LMNA (0.53) MEN1CYP1A2MAPTCYP2C19KMT2A
SCHEMBL9002299 0.69 MAPK1 (0.34) MEN1CYP1A2CYP3A4MAPTCYP2C9
SCHEMBL12774894 0.69 TSHR (0.41) MEN1CYP1A2CYP3A4MAPTCYP2C9
SCHEMBL9002281 0.68 TSHR (0.46) HSP90AA1MEN1CYP1A2CYP3A4MAPT
SCHEMBL13232706 0.68 KIF11 (0.51) RORCMEN1CYP1A2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 — — US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 — — US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 — — US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 — — US disclosed
US-8377344-B2 comprising thermoplastic resins or cellulose acetates, mixed with sulfonamides or tertiary amides, used as protecting coatings for polarizing plates and as adjustment films for display panels to improve viewing angles FUJIFILM CORPORATION (JP) 2013-02-19 — — US disclosed
US-20080138541-A1 Optical Film, Method for Producing Optical Film, Optically-Compensatory Film, Polarizing Plate and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 — — US disclosed
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