Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.40 |
| ▸ | CSNK1G2 | P78368 | 4/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CFB | P00751 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022011 | 0.80 | AHR (0.47) | L3MBTL1CSNK1DCSNK1G2CSNK1A1GSK3B | |
| SCHEMBL6007662 | 0.74 | CHUK (0.53) | L3MBTL1ITKALDH1A1CYP2A6MAPK10 | |
| SCHEMBL6008260 | 0.74 | KIF11 (0.58) | L3MBTL1CSNK1DCSNK1G2CSNK1A1GSK3B | |
| SCHEMBL28300282 | 0.73 | ALK (0.41) | L3MBTL1CSNK1DCSNK1G2CSNK1A1GSK3B | |
| SCHEMBL10481569 | 0.72 | KDM4E (0.49) | L3MBTL1ITKALDH1A1ALKNOS3 | |
| SCHEMBL29894052 | 0.71 | KDM4E (0.59) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL4736477 | 0.71 | KDM4E (0.59) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL13243050 | 0.70 | ITK (0.41) | L3MBTL1CSNK1DCSNK1G2CSNK1A1GSK3B | |
| SCHEMBL14214508 | 0.70 | AHR (0.57) | L3MBTL1ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL12377872 | 0.69 | SLC6A4 (0.48) | ITKALDH1A1CYP2A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | ADRB2, ADRB1, ADRA2C | L3MBTL1 3143/4885CSNK1D 49/4885CSNK1G2 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.