Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215938 | 0.81 | CA2 (0.35) | HSD11B1MEN1KMT2ACA2 | |
| SCHEMBL14215939 | 0.75 | BCAT2 (0.38) | HSD11B1BCAT2LOXCA2DRD2 | |
| SCHEMBL8106699 | 0.71 | LOX (0.47) | HSD11B1BCAT2LOXCA2ACLY | |
| SCHEMBL14215940 | 0.71 | BCAT2 (0.39) | HSD11B1BCAT2LOXACLYDRD2 | |
| SCHEMBL515098 | 0.69 | KMT2A (0.56) | HSD11B1MEN1KMT2A | |
| SCHEMBL1542687 | 0.66 | CA1 (0.62) | HSD11B1POLBBCAT2KMT2ALOX | |
| SCHEMBL29890712 | 0.66 | CA1 (0.62) | HSD11B1POLBBCAT2KMT2ALOX | |
| SCHEMBL514170 | 0.66 | ALDH1A1 (0.44) | HSD11B1KMT2AACLY | |
| SCHEMBL17145370 | 0.66 | ELANE (0.48) | HSD11B1BCAT2LOXCA2ACLY | |
| SCHEMBL14215942 | 0.65 | CA2 (0.35) | HSD11B1MEN1KMT2ACA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378154-B2 | Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes | DAIKIN INDUSTRIES, LTD. (JP) | 2008-05-27 | — | — | US | disclosed |