SCHEMBL14215939

SCHEMBL14215939

CPc1ccccc1S(C)(=O)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.38
LOX P28300 1/20 0.35
DRD2 P14416 1/20 0.34
HSD11B1 P28845 1/20 0.34
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
PTK2 Q05397 1/20 0.34
GAA P10253 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ADRA1A P35348 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RAB9A P51151 1/20 0.33
BRD9 Q9H8M2 1/20 0.33
BAZ2B Q9UIF8 1/20 0.33
BAZ2A Q9UIF9 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536158 0.80 MYC (0.44) GAAALDH1A1SMN1; SMN2KDM4EL3MBTL1
SCHEMBL8106699 0.77 LOX (0.47) BCAT2LOXDRD2HSD11B1GAA
SCHEMBL14215940 0.77 BCAT2 (0.39) BCAT2LOXDRD2HSD11B1LMNA
SCHEMBL14421058 0.77 HTR6 (0.52) HSD11B1GAAALDH1A1HTTKDM4E
SCHEMBL14215942 0.75 CA2 (0.35) HSD11B1ALDH1A1LMNACA1CA2
SCHEMBL14215941 0.75 HSD11B1 (0.35) BCAT2LOXDRD2HSD11B1LMNA
SCHEMBL7894960 0.71 TSHR (0.35) LMNACA1CA2CA4CA12
SCHEMBL12307 0.69 L3MBTL1 (0.50) BCAT2HSD11B1ALDH1A1TP53KDM4E
SCHEMBL670704 0.69 BCAT2 (0.41) BCAT2LOXDRD2HSD11B1GAA
SCHEMBL28278788 0.69 L3MBTL1 (0.50) BCAT2HSD11B1ALDH1A1TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed