Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.62 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425314 | 0.92 | ALDH1A1 (0.60) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL21156471 | 0.91 | ALDH1A1 (0.55) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL5216212 | 0.90 | ALDH1A1 (0.58) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL13258617 | 0.89 | ALDH1A1 (0.57) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL14953129 | 0.89 | ALDH1A1 (0.57) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL3842399 | 0.89 | ALDH1A1 (0.57) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL972755 | 0.87 | ALDH1A1 (0.76) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL15853568 | 0.86 | ALDH1A1 (0.61) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL16472557 | 0.86 | ALDH1A1 (0.61) | ALDH1A1AOX1FDPSHPGDTDP1 | |
| SCHEMBL662141 | 0.86 | ALDH1A1 (0.75) | ALDH1A1AOX1FDPSHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031253-B1 | PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | claimed |
| EP-0031253-A1 | Process for preparing 3,4-substituted benzaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-07-01 | — | — | EP | claimed |
| US-20230303561-A1 | PYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN RESISTING MYCOBACTERIUM TUBERCULOSIS INFECTION | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230248837-A1 | Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof | LIU, MIAO (CN) | 2023-08-10 | — | — | US | disclosed |
| CN-114081890-B | Application of pyrimidinone derivative in resisting tubercle bacillus infection | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | disclosed |
| EP-4180429-A1 | PYRIMIDINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF AGAINST MYCOBACTERIUM TUBERCULOSIS INFECTION | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2023-05-17 | — | — | EP | disclosed |
| CN-114081890-A | Application of pyrimidone derivatives in resisting mycobacterium tuberculosis infection | 中国医学科学院医药生物技术研究所 | 2022-02-25 | — | — | CN | disclosed |
| CN-111925368-B | Pyrimidone derivatives, preparation method thereof and application thereof in resisting mycobacterium tuberculosis infection | 中国医学科学院医药生物技术研究所 | 2021-11-05 | — | — | CN | disclosed |
| CN-111925368-A | Pyrimidone derivatives, preparation method thereof and application thereof in resisting mycobacterium tuberculosis infection | 中国医学科学院医药生物技术研究所 | 2020-11-13 | — | — | CN | disclosed |
| EP-2984077-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | Chromocell Corporation (US) | 2016-02-17 | — | — | EP | disclosed |
| US-20160015064-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORPORATION (US) | 2016-01-21 | — | — | US | disclosed |
| CN-1241176-A | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER (US) | 2000-01-12 | — | — | CN | disclosed |
| EP-0946501-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1998028264-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| US-4587356-A | Process for the production of nuclear substituted cinnamoylanthranilic acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1986-05-06 | — | — | US | disclosed |
| EP-0031253-B1 | PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4335263-A | MANY STEPS, STARTING WITH ACETYLATION OF M-CRESOL OR P-CRESOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-15 | — | — | US | disclosed |
| EP-0031253-A1 | Process for preparing 3,4-substituted benzaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-07-01 | — | — | EP | disclosed |
| US-3932678-A | Novel dihydrochalcone sweetener compositions | THE PROCTER & GAMBLE COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303561-A1 | PYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN RESISTING MYCOBACTERIUM TUBERCULOSIS INFECTION | DHPS, DHFR, QDPR | ALDH1A1 234/4885AOX1 1509/4885FDPS 14/4885 |
| US-20160015064-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | TAS2R5, TAS2R20, TAS2R10 | ALDH1A1 2420/4885AOX1 2583/4885FDPS 587/4885 |
| US-20230248837-A1 | Technology for Modulating Targeting Chimeras Induced by Cell-Penetrating Peptide and Application Thereof | VIP, GHITM, MYCBP | ALDH1A1 4851/4885AOX1 4755/4885FDPS 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.