Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425713 | 0.86 | MAOB (0.50) | RAB9ASMN1; SMN2GAAMEN1NPC1 | |
| SCHEMBL222716 | 0.80 | PARP10 (0.51) | GAAMGAMSIMGAM2GSTP1 | |
| SCHEMBL12811783 | 0.78 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1POLBLMNA | |
| SCHEMBL3649527 | 0.77 | NR4A2 (0.56) | MEN1KMT2AGSTP1PRMT5MAOB | |
| SCHEMBL1425556 | 0.77 | ADORA3 (0.50) | RAB9ASMN1; SMN2GAANPC1PTGS2 | |
| SCHEMBL13258018 | 0.73 | GSTP1 (0.58) | RAB9ASMN1; SMN2GAAGSTP1MAOB | |
| SCHEMBL1425593 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2APRMT5MAOBLMNA | |
| SCHEMBL197017 | 0.72 | LMNA (0.72) | RAB9ASMN1; SMN2GAAMEN1NPC1 | |
| SCHEMBL1425924 | 0.71 | NPC1 (0.46) | RAB9ASMN1; SMN2MEN1NPC1KMT2A | |
| SCHEMBL4107347 | 0.71 | RXFP1 (0.40) | RAB9ASMN1; SMN2MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492414-B2 | Antibacterial agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-07-23 | — | — | US | disclosed |
| US-8492414-B2 | Antibacterial agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-07-23 | — | — | US | disclosed |
| EP-2200991-B1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-03-23 | — | — | EP | disclosed |
| US-20100273837-A1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD. (GB) | 2010-10-28 | — | — | US | disclosed |
| US-20100273837-A1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD. (GB) | 2010-10-28 | — | — | US | disclosed |
| EP-2200991-A1 | ANTIBACTERIAL AGENTS | Biota Europe Ltd (GB) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009037485-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273837-A1 | ANTIBACTERIAL AGENTS | SQOR, SCO2, CYCS | RAB9A 840/4885SMN1; SMN2 3787/4885GAA 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.