Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716643 | 0.74 | TSHR (0.43) | ALDH1A1KDM4EHSD17B10TSHRMRGPRX4 | |
| SCHEMBL31045837 | 0.72 | MTNR1A (0.44) | ALDH1A1KDM4EHSD17B10TSHRIMPDH2 | |
| SCHEMBL27621906 | 0.71 | ALOX5 (0.38) | ALDH1A1KDM4EHSD17B10TSHRIMPDH2 | |
| SCHEMBL28829137 | 0.71 | GPR55 (0.45) | ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL13034124 | 0.70 | TAAR1 (0.43) | ALDH1A1KDM4ETSHRIMPDH2KMT2A | |
| SCHEMBL11484541 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10TSHRKMT2A | |
| SCHEMBL28519470 | 0.68 | KDM4A (0.47) | ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL4374949 | 0.67 | L3MBTL1 (0.59) | ALDH1A1PKMKMT2A | |
| SCHEMBL28659748 | 0.67 | KMT2A (0.35) | ALDH1A1KDM4EPKMKMT2AGAA | |
| SCHEMBL20460826 | 0.66 | ALDH1A1 (0.71) | ALDH1A1KDM4EHSD17B10TSHRMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724110-B1 | Multilayered articles and method of manufacture thereof | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-08-21 | — | — | EP | disclosed |
| EP-2300414-B1 | METHOD FOR PRODUCING PHENOLIC COMPOUND | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-04-27 | — | — | EP | disclosed |
| EP-1414779-B1 | SOLVENTLESS PREPARATION OF ESTER-SUBSTITUTED DIARYL CARBONATES | SABIC INNOVATIVE PLASTICS IP (NL) | 2015-05-27 | — | — | EP | disclosed |
| US-8900693-B2 | Polycarbonate compositions having infrared absorbance, method of manufacture, and articles prepared therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2014-12-02 | — | — | US | disclosed |
| EP-1907465-B1 | POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-07-23 | — | — | EP | disclosed |
| EP-1776332-B1 | METHOD OF PREPARING ESTER-SUBSTITUTED DIARYL CARBONATES | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-07-03 | — | — | EP | disclosed |
| EP-1529632-B1 | Multilayered articles and method of manufacture thereof | SABIC INNOVATIVE PLASTICS IP (NL) | 2012-09-05 | — | — | EP | disclosed |
| US-8034967-B2 | Method of preparing a purified ester-substituted phenol stream | Sabic Innnovative Plastics IP B.V. (NL) | 2011-10-11 | — | — | US | disclosed |
| EP-2215045-B1 | METHOD OF PREPARING A PURIFIED ESTER-SUBSTITUTED PHENOL STREAM | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-08-03 | — | — | EP | disclosed |
| EP-2300414-A1 | METHOD FOR PRODUCING PHENOLIC COMPOUND | SABIC Innovative Plastics IP B.V. (NL) | 2011-03-30 | — | — | EP | disclosed |
| US-20030149223-A1 | Method of polycarbonate preparation | GENERAL ELECTRIC COMPANY | 2003-08-07 | — | — | US | disclosed |
| US-6548623-B2 | Melt reaction of bisphenol A and bis-methyl salicyl carbonate using alkali or alkaline earth metal catalyst and quaternary ammonium or phosphonium compound; Fries suppression; by-product inhibition | GENERAL ELECTRIC COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-20030060649-A1 | Solventless preparation of ester-substituted diaryl carbonates | GENERAL ELECTRIC COMPANY | 2003-03-27 | — | — | US | disclosed |
| US-20030050427-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY | 2003-03-13 | — | — | US | disclosed |
| WO-2003010218-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |
| WO-2003010123-A1 | SOLVENTLESS PREPARATION OF ESTER-SUBSTITUTED DIARYL CARBONATES | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |
| WO-2003010122-A1 | INTERFACIAL METHOD OF PREPARING ESTER-SUBSTITUTED DIARYL CARBONATES | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |
| US-6469192-B1 | NO SOLVENT OTHER THAN WATER OR STARTING ESTER- SUBSTITUTED PHENOL IS PRESENT IN THE REACTION MIXTURE DURING THE REACTION OF ESTER-SUBSTITUTED PHENOL WITH PHOSGENE | GENERAL ELECTRIC COMPANY | 2002-10-22 | — | — | US | disclosed |
| US-6420512-B1 | SCREW EXTRUSION AND ESTER INTERCHANGE | GENERAL ELECTRIC COMPANY | 2002-07-16 | — | — | US | disclosed |
| US-6420588-B1 | REACTION OF PHENOL WITH PHOSGENE AND PHASE TRANSFER AGENT | GENERAL ELECTRIC COMPANY | 2002-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060649-A1 | Solventless preparation of ester-substituted diaryl carbonates | CDS2, ASH2L, PGGT1B | ALDH1A1 4720/4885KDM4E 339/4885HSD17B10 1755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.