Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | FOS | P01100 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022512 | 0.85 | ALDH1A1 (0.38) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL27930394 | 0.79 | TUBB4A (0.46) | FOSTTRJUNAKR1B1CA2 | |
| SCHEMBL724406 | 0.78 | PTGS2 (0.59) | CA2PTGS2CYP3A4MAPT | |
| SCHEMBL4576587 | 0.78 | PTGS2 (0.59) | ALDH1A1PDE3BPDE3AFOSTTR | |
| SCHEMBL918818 | 0.78 | FOS (0.39) | ALDH1A1KDM4EPDE3BPDE3AFOS | |
| SCHEMBL14262201 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL2448637 | 0.76 | PRKDC (0.42) | ALDH1A1PPARGPPARDPPARAKDM4E | |
| SCHEMBL918844 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EPDE3BPDE3ATTR | |
| SCHEMBL4054977 | 0.76 | MAPT (0.51) | KDM4EAKR1B1CA2PTGS2CYP3A4 | |
| SCHEMBL918623 | 0.76 | THRB (0.44) | FOSTTRJUNNR3C1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | disclosed |
| US-7321050-B2 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH INC. (CA) | 2008-01-22 | — | — | US | disclosed |