SCHEMBL4054977

SCHEMBL4054977

COc1cc(CC=O)cc(OC)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
LMNA P02545 2/20 0.51
TNKS2 Q9H2K2 2/20 0.51
TNKS O95271 1/20 0.51
MET P08581 2/20 0.49
AKR1B1 P15121 1/20 0.49
PKM P14618 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
ALOX5 P09917 1/20 0.47
GAA P10253 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14262143 0.90 TNKS2 (0.47) MAPTLMNATNKS2TNKSMET
SCHEMBL14262144 0.87 LMNA (0.69) MAPTLMNAERN1
SCHEMBL8916819 0.87 TRPV1 (0.49) MAPTLMNATNKS2TNKSMET
SCHEMBL27943237 0.83 MAPT (0.45) MAPTLMNATNKS2TNKSMET
SCHEMBL15238542 0.82 AKR1B1 (0.53) MAPTLMNATNKS2METAKR1B1
SCHEMBL15649780 0.82 RAB9A (0.56) MAPTLMNAERN1CYP2D6KDM4E
Methoxyeugenol SCHEMBL293977 0.82 TNKS (0.73) MAPTLMNATNKS2TNKSAKR1B1
SCHEMBL724406 0.81 PTGS2 (0.59) MAPTCA12CA1CA2CA9
SCHEMBL30203242 0.80 TNKS2 (0.53) MAPTLMNATNKS2TNKSMET
SCHEMBL27726736 0.80 TNKS2 (0.49) MAPTLMNATNKS2TNKSMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595369-B2 Algae-resistant bitumen-containing materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-04-07 US claimed
US-20240367148-A1 BIO-GRAFTED SILICA AS AN ADSORBENT OF VOLATILE ORGANIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-11-07 US claimed
US-20230193033-A1 ALGAE-RESISTANT BITUMEN-CONTAINING MATERIALS NATIONAL SCIENCE FOUNDATION 2023-06-22 US claimed
WO-2013173332-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN Vertichem Corporation (CA) 2013-11-21 WO claimed
US-20130232853-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US claimed
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US claimed
WO-2013134756-A1 A METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN Vertichem Corporation (CA) 2013-09-12 WO claimed
US-12595369-B2 Algae-resistant bitumen-containing materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-04-07 US disclosed
EP-4680731-A2 METHOD FOR PRODUCING LIGNIN-HEMICELLULOSE HYBRID NANOPARTICLES OR LIGNIN NANOPARTICLES Helsingin Yliopisto (FI) 2026-01-21 EP disclosed
US-12435345-B2 Prehydrolysate fermentability in biomass pretreatment UNIVERSITY OF CINCINNATI (US) 2025-10-07 US disclosed
US-20240367148-A1 BIO-GRAFTED SILICA AS AN ADSORBENT OF VOLATILE ORGANIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-11-07 US disclosed
WO-2024194524-A2 METHOD FOR PRODUCING LIGNIN-HEMICELLULOSE HYBRID NANOPARTICLES OR LIGNIN NANOPARTICLES HELSINGIN YLIOPISTO (FI) 2024-09-26 WO disclosed
US-11788228-B2 Methods for processing lignocellulosic material CMBLU ENERGY AG (DE) 2023-10-17 US disclosed
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US disclosed
WO-2013090892-A1 SUBSTITUTED PHENACYL MOLECULES AND PHOTORESPONSIVE POLYMERS THE UNIVERSITY OF AKRON (US) 2013-06-20 WO disclosed
WO-2009117555-A1 FLORAL DIP METHOD FOR TRANSFORMATION OF CAMELINA TARGETED GROWTH, INC. (US) 2009-09-24 WO disclosed
US-7524836-B2 Nitrooxyderivative steroidal compounds NICOX S.A. (FR) 2009-04-28 US disclosed
US-20070142342-A1 Pharmaceutical compounds NICOX S.A. 2007-06-21 US disclosed
EP-1331975-A1 SOLVENT EXTRACTION PROCESS Ineos Fluor Holdings Limited (GB) 2003-08-06 EP disclosed
WO-2002036232-A1 SOLVENT EXTRACTION PROCESS INEOS FLUOR HOLDINGS LIMITED (GB) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142342-A1 Pharmaceutical compounds CYP11B2, CYP11B1, CYP2S1 MAPT 3031/4885LMNA 3381/4885TNKS2 2698/4885
US-11788228-B2 Methods for processing lignocellulosic material DCXR, LCT, AGL MAPT 1450/4885LMNA 109/4885TNKS2 977/4885
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN DCXR, AGL, GLO1 MAPT 463/4885LMNA 698/4885TNKS2 1491/4885
US-12595369-B2 Algae-resistant bitumen-containing materials BECN1, SFN, DEK MAPT 611/4885LMNA 4500/4885TNKS2 1479/4885
US-20130232853-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN HAAO, HAO2, HACL2 MAPT 2625/4885LMNA 1448/4885TNKS2 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.