Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | BLM | P54132 | 5/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13528568 | 0.68 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL6823378 | 0.67 | METAP2 (0.53) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL63014 | 0.67 | RAB9A (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2675050 | 0.67 | KDM4E (0.43) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL7469550 | 0.67 | POLB (0.48) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL1201957 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL2692514 | 0.67 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL3060017 | 0.66 | KDM4E (0.58) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL31064975 | 0.66 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTBLMPDE10A | |
| SCHEMBL1671486 | 0.65 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTBLMPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116896913-A | Light-emitting device including heterocyclic compound, electronic apparatus, and heterocyclic compound | 三星显示有限公司 | 2023-10-17 | — | — | CN | claimed |
| US-20060167046-A1 | Histamine h3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY PATENT DIVISION (US) | 2006-07-27 | — | — | US | claimed |
| EP-1585731-A2 | HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-10-19 | — | — | EP | claimed |
| WO-2004026837-A2 | HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2004-04-01 | — | — | WO | claimed |
| US-6046204-A | Pyrrolo[3,4-D] pyrimidinone derivatives and their use as medicaments | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-04-04 | — | — | US | claimed |
| CN-118265786-A | Microtubule-associated protein Tau (MAPT) iRNA pharmaceutical compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20240166637-A1 | COMPOUNDS AND METHODS FOR TREATING MALARIA | MICROBIOTIX, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | VANDERBILT UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| EP-4281077-A1 | COMPOUNDS AND METHODS FOR TREATING MALARIA | Microbiotix, Inc. (US) | 2023-11-29 | — | — | EP | disclosed |
| CN-116471860-A | Light emitting device and electronic apparatus including the same | 三星显示有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-20200390099-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | UNIV VANDERBILT (US) | 2020-12-17 | — | — | US | disclosed |
| EP-2875005-B1 | N-(3-HETEROARYLARYL)-4-ARYLARYLCARBOXAMTDES AND ANALOGS AS HEDGEHOG PATHWAY INHIBITORS AND USE THEREOF | IMPACT THERAPEUTICS INC (CN) | 2020-11-11 | — | — | EP | disclosed |
| WO-2004069829-A1 | (2S)-2-((PYRIMIDIN-4-YL)AMINO)-4-METHYLPENTANOIC ACID AMINOETHYLAMID DERIVATIVES AS IL-8 RECEPTOR MODULATORS FOR THE TREATMENT OF ATHEROSCLEROSIS AND RHEUMATOID ARTHRITIS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004062609-A2 | PYRIMIDINE DERIVATIVES AS IL-8 RECEPTOR ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-1420879-A2 | TREATMENT OF SUBSTRATES USING AN ELECTROCHEMICAL METHOD | ISIS INNOVATION LIMITED (GB) | 2004-05-26 | — | — | EP | disclosed |
| US-20040087601-A1 | Pyrimidine derivatives as IL-8 receptor antagonists | PHARMACOPEIA, LLC | 2004-05-06 | — | — | US | disclosed |
| WO-2004026837-A2 | HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2004-04-01 | — | — | WO | disclosed |
| WO-2003020415-A2 | TREATMENT OF SUBSTRATES USING AN ELECTROCHEMICAL METHOD | ISIS INNOVATION LIMITED (GB) | 2003-03-13 | — | — | WO | disclosed |
| US-6136974-A | Pyrrolo[3,4-D]Pyrimidinone derivatives and their use as medicaments | ASTRAZENECA UK LIMITED (GB) | 2000-10-24 | — | — | US | disclosed |
| CN-1037340-A | 1-dimethylin formyl radical-3-replacement-5-replacement-1H-1,2, the 4-triazole | ROHM & HAAS (US) | 1989-11-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11856955-B2 | Binary compositions as disruptors of Orco-mediated odorant sensing | OR51E2, OR10J3, ORC3 | ALDH1A1 2481/4885KDM4E 3247/4885MAPT 2247/4885 |
| US-20040087601-A1 | Pyrimidine derivatives as IL-8 receptor antagonists | CXCL8, IL1RN, IL18 | ALDH1A1 1217/4885KDM4E 4646/4885MAPT 4048/4885 |
| US-20240166637-A1 | COMPOUNDS AND METHODS FOR TREATING MALARIA | PORCN, VDAC1, VDAC2 | ALDH1A1 1663/4885KDM4E 3180/4885MAPT 2087/4885 |
| US-20200390099-A1 | BINARY COMPOSITIONS AS DISRUPTORS OF ORCO-MEDIATED ODORANT SENSING | OR51E2, OR10J3, ORC3 | ALDH1A1 2481/4885KDM4E 3247/4885MAPT 2247/4885 |
| US-20060167046-A1 | Histamine h3 receptor antagonists, preparation and therapeutic uses | HRH3, HRH4, HRH2 | ALDH1A1 1573/4885KDM4E 620/4885MAPT 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.