Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14300476 | 0.90 | TNIK (0.43) | TNIKRPS6KA3GRM4RPS6KA6AURKA | |
| SCHEMBL14293828 | 0.79 | RAB9A (0.44) | RPS6KA6TNK2SYK | |
| SCHEMBL14293956 | 0.76 | RAB9A (0.53) | RPS6KA6MAPT | |
| SCHEMBL14300020 | 0.74 | TXN (0.54) | TNIKGRM4APPKDM4EMAPT | |
| SCHEMBL14294396 | 0.74 | APP (0.56) | TNIKAPPMAPT | |
| SCHEMBL14300477 | 0.73 | GALR1 (0.49) | RPS6KA3RPS6KA6TNK2CDK1CDK4 | |
| SCHEMBL655309 | 0.71 | SYK (0.70) | RPS6KA3AURKASYKCDK1CDK2 | |
| SCHEMBL13578882 | 0.69 | EGFR (0.42) | TNIKGRM4AURKAKDM4EMAPT | |
| SCHEMBL4839000 | 0.67 | CTSL (0.56) | APPCDK1CDK4CCNB1CCND1 | |
| SCHEMBL13632608 | 0.67 | GRM4 (0.46) | TNIKGRM4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332489-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332490-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |