Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312631 | 0.92 | KDM4E (0.31) | KDM4EALDH1A1HPGD | |
| SCHEMBL14312689 | 0.90 | HPGDS (0.35) | KDM4EALDH1A1HPGDTYK2 | |
| SCHEMBL14312986 | 0.89 | TGFBR1 (0.35) | KDM4EALDH1A1HPGDPDE4AKCNH2 | |
| SCHEMBL14313173 | 0.88 | PDE4A (0.30) | KDM4EALDH1A1HPGDPDE4AKCNH2 | |
| SCHEMBL14313264 | 0.86 | HPGDS (0.38) | KDM4EALDH1A1HPGD | |
| SCHEMBL14312869 | 0.85 | CES2 (0.31) | — | |
| SCHEMBL14312961 | 0.85 | AGTR2 (0.30) | — | |
| SCHEMBL14313272 | 0.85 | AGTR2 (0.30) | — | |
| SCHEMBL14312794 | 0.84 | HPGDS (0.31) | — | |
| SCHEMBL14312879 | 0.82 | ENPP3 (0.36) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |