Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434992 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1PPIBL3MBTL1 | |
| SCHEMBL1433071 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1PPIBL3MBTL1 | |
| SCHEMBL1432276 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1PPIBSCN5A | |
| SCHEMBL1432596 | 0.76 | MASP2 (0.39) | F2R | |
| SCHEMBL1432168 | 0.75 | MASP2 (0.35) | F2R | |
| SCHEMBL1431525 | 0.74 | PPIB (0.39) | ALDH1A1PPIBSMN1; SMN2 | |
| SCHEMBL23419975 | 0.74 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL1431838 | 0.74 | METAP2 (0.39) | — | |
| SCHEMBL1901816 | 0.73 | MASP2 (0.39) | F2R | |
| SCHEMBL1431936 | 0.73 | F2 (0.39) | ALDH1A1PPIBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |