Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15805914 | 0.83 | ASH1L (0.47) | CYP1A2 | |
| M-Xylene SCHEMBL28015969 | 0.80 | ACHE (0.67) | PARP1CYP1A2FAAHALDH1A1GAA | |
| SCHEMBL1411277 | 0.79 | PARP1 (0.54) | PARP1CYP1A2FAAHALDH1A1MAPT | |
| SCHEMBL9528530 | 0.79 | PARP1 (0.54) | PARP1CYP1A2FAAHCTSLALDH1A1 | |
| M-Xylene SCHEMBL27788949 | 0.78 | ACHE (0.63) | PARP1CYP1A2FAAHALDH1A1GAA | |
| SCHEMBL13680641 | 0.78 | HSD17B1 (0.50) | PARP1CYP1A2ALDH1A1GAAMAPT | |
| SCHEMBL11122251 | 0.78 | PARP1 (0.53) | PARP1CYP1A2FAAHCTSLCTSK | |
| SCHEMBL11122254 | 0.78 | PARP1 (0.53) | PARP1CYP1A2FAAHCTSLCTSK | |
| SCHEMBL13799999 | 0.77 | PARP1 (1.00) | PARP1MAPTHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL2687704 | 0.77 | PARP1 (0.63) | PARP1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116256450-A | Method for distinguishing acerola cherry fruit powder from acerola cherry juice powder and screening method of characteristic markers of acerola cherry fruit powder | 中国农业科学院农业质量标准与检测技术研究所 | 2023-06-13 | — | — | CN | claimed |
| CN-114990587-B | Electrochemical synthesis method of thiazole compound | 华南理工大学 | 2023-05-23 | — | — | CN | claimed |
| CN-114990587-A | Electrochemical synthesis method of thiazole compound | 华南理工大学 | 2022-09-02 | — | — | CN | claimed |
| CN-116256450-A | Method for distinguishing acerola cherry fruit powder from acerola cherry juice powder and screening method of characteristic markers of acerola cherry fruit powder | 中国农业科学院农业质量标准与检测技术研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-114990587-B | Electrochemical synthesis method of thiazole compound | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| US-11472815-B2 | 1,4-diphenyl-1H-imidazole and 2,4-diphenylthiazole derivatives and preparation method therefor and use thereof | SOUTHERN MEDICAL UNIVERSITY (CN) | 2022-10-18 | — | — | US | disclosed |
| CN-114990587-A | Electrochemical synthesis method of thiazole compound | 华南理工大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-110511233-B | Thiazolo [2,3-b ] oxazolone compound and preparation method and application thereof | 成都大学 | 2022-01-25 | — | — | CN | disclosed |
| US-11046662-B2 | 2-aryl-4-hydroxy-1,3-thiazole derivatives useful as TRPM8-inhibitors in treatment of neuralgia, pain, COPD and asthma | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2021-06-29 | — | — | US | disclosed |
| US-20210017189-A1 | 1,4-DIPHENYL-1H-IMIDAZOLE AND 2,4-DIPHENYLTHIAZOLE DERIVATIVES AND PREPARATION METHOD THEREFOR AND USE THEREOF | SOUTHERN MEDICAL UNIVERSITY (CN) | 2021-01-21 | — | — | US | disclosed |
| CN-110981850-B | Green preparation method of thioamide | 华南农业大学 | 2020-11-13 | — | — | CN | disclosed |
| EP-1402900-A1 | MEDICINAL COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1354603-A1 | CONCOMITANT DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-20030130281-A1 | DPP IV inhibitors | HOFFMAN-LA ROCHE INC. | 2003-07-10 | — | — | US | disclosed |
| WO-2003037327-A1 | N-SUBSTITUTED PYRROLIDIN DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | F. HOFFMANN-LA-ROCHE AG (CH) | 2003-05-08 | — | — | WO | disclosed |
| EP-1205478-A1 | p38MAP KINASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11472815-B2 | 1,4-diphenyl-1H-imidazole and 2,4-diphenylthiazole derivatives and preparation method therefor and use thereof | TLR1, TLR4, TLR3 | PARP1 3490/4885CYP1A2 3560/4885FAAH 457/4885 |
| US-11046662-B2 | 2-aryl-4-hydroxy-1,3-thiazole derivatives useful as TRPM8-inhibitors in treatment of neuralgia, pain, COPD and asthma | TRPM8, TRPV1, TRPM7 | PARP1 4068/4885CYP1A2 916/4885FAAH 250/4885 |
| US-20210017189-A1 | 1,4-DIPHENYL-1H-IMIDAZOLE AND 2,4-DIPHENYLTHIAZOLE DERIVATIVES AND PREPARATION METHOD THEREFOR AND USE THEREOF | TLR1, TLR4, TLR3 | PARP1 3490/4885CYP1A2 3560/4885FAAH 457/4885 |
| US-20030130281-A1 | DPP IV inhibitors | DPP4, DPP3, DPP7 | PARP1 1383/4885CYP1A2 655/4885FAAH 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.