Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21086644 | 0.81 | LMNA (0.40) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL12629758 | 0.67 | MAOA (0.37) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL21065789 | 0.66 | GPR3 (0.44) | LMNAALDH1A1MEN1KMT2AATM | |
| SCHEMBL7570833 | 0.65 | BRD4 (0.42) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11155913 | 0.64 | BRD4 (0.49) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL27550145 | 0.63 | MAOA (0.38) | LMNAALDH1A1SMN1; SMN2TDP1DRD2 | |
| SCHEMBL27988028 | 0.63 | LMNA (0.34) | LMNAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL14454336 | 0.61 | PGR (0.40) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11467446 | 0.61 | MAOA (0.32) | LMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL15535721 | 0.61 | MAOA (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | claimed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | claimed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | claimed |
| US-9603354-B2 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| US-7977383-B2 | Containing alkali ions, electrolytes, a buffer, polyol, saccharide and hydroxamic acid derivatives | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| EP-1362511-B1 | Protective solution for preventing ischaemia | KOEHLER CHEMIE DR FRANZ (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-1859679-B1 | Protective solution for preventing ischaemia damage | KOEHLER CHEMIE DR FRANZ (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-1859679-A1 | Protective solution for preventing ischaemia damage | Dr. Franz Köhler Chemie GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-20030215781-A1 | Protective solutions for organs | DR. FRANZ KOEHLER CHEMIE GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-1362511-A1 | Protective solution for preventing ischaemia | Dr. Franz Köhler Chemie GmbH (DE) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030215781-A1 | Protective solutions for organs | GLS, CA1, SI | LMNA 3116/4885ALDH1A1 1929/4885SMN1; SMN2 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.