Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 4/20 | 0.54 |
| ▸ | MMP2 | P08253 | 4/20 | 0.54 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227304 | 0.91 | BACE1 (0.56) | TRPM2MAPTGAABACE1MMP1 | |
| SCHEMBL111339 | 0.90 | TRPM2 (0.65) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL13556323 | 0.86 | TRPA1 (0.69) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL14227336 | 0.85 | TRPA1 (0.55) | TRPM2MAPTGAABACE1MMP1 | |
| SCHEMBL18230842 | 0.85 | TRPM2 (0.64) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL27478826 | 0.84 | MAPT (0.73) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL14227307 | 0.82 | MEN1 (0.59) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL14515853 | 0.81 | MMP1 (0.64) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL14227322 | 0.81 | MMP1 (0.55) | TRPM2MAPTGAAMMP1MMP2 | |
| SCHEMBL11236190 | 0.81 | MEN1 (0.75) | TRPM2MAPTGAASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150258003-A1 | HAND SANITIZERS WITH IMPROVED AESTHETICS AND SKIN-CONDITING TO ENCOURAGE COMPLIANCE WITH HAND HYGIENE GUIDELINES | SILVER POINT FINANCE, LLC, AS COLLATERAL AGENT | 2015-09-17 | — | — | US | disclosed |
| US-20070264362-A1 | Method and composition for treating ear inflammation caused by dry ear | YOSHPE NINA | 2007-11-15 | — | — | US | disclosed |
| US-20070185038-A1 | Regulation of mammalian keratinous tissue using skin care actives | THE PROCTER & GAMBLE COMPANY | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070264362-A1 | Method and composition for treating ear inflammation caused by dry ear | ALOX5, ALOX15, ALOX12 | TRPM2 911/4885MAPT 4694/4885GAA 4584/4885 |
| US-20150258003-A1 | HAND SANITIZERS WITH IMPROVED AESTHETICS AND SKIN-CONDITING TO ENCOURAGE COMPLIANCE WITH HAND HYGIENE GUIDELINES | CUTA, HAAO, HAO1 | TRPM2 4512/4885MAPT 3919/4885GAA 1240/4885 |
| US-20070185038-A1 | Regulation of mammalian keratinous tissue using skin care actives | CUTA, KDM7A, KDM2A | TRPM2 1163/4885MAPT 3610/4885GAA 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.