SCHEMBL13435233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14367128	0.81	KMT2A (0.52)	CA2HSD17B10ALDH1A1HPGDLMNA
	SCHEMBL14341653	0.80	HPGD (0.46)	CA2ALDH1A1HPGDLMNAGAA
	SCHEMBL6541372	0.79	CA2 (0.47)	CA2CAMK2AAKR1B1HSD17B10ALDH1A1
	SCHEMBL46640	0.79	CA2 (0.56)	CA2CAMK2AAKR1B1HSD17B10ALDH1A1
	SCHEMBL21328439	0.79	ACHE (0.50)	CA2ALDH1A1HPGDLMNAKDM4E
	SCHEMBL14490064	0.79	NOS3 (0.39)	CA2ALDH1A1HPGDLMNATSHR
	SCHEMBL13464286	0.79	CA2 (0.60)	CA2CAMK2AAKR1B1HSD17B10ALDH1A1
	SCHEMBL225546	0.79	CA2 (0.60)	CA2CAMK2AAKR1B1HSD17B10ALDH1A1
	SCHEMBL10187470	0.78	LMNA (0.58)	CA2ALDH1A1HPGDLMNA
	SCHEMBL10587186	0.78	CES2 (0.42)	CA2ALDH1A1HPGDLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.