Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13981150 | 1.00 | ACHE (0.55) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL26762470 | 0.96 | ACHE (0.57) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL26762465 | 0.94 | ACHE (0.53) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL4401614 | 0.91 | CHRM5 (0.48) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL26762595 | 0.88 | ACHE (0.52) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL15499060 | 0.88 | ACHE (0.42) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL25959923 | 0.85 | ACHE (0.46) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL26762522 | 0.85 | ACHE (0.50) | ACHECHRM5ADRA2CCARM1PRMT6 | |
| SCHEMBL15217800 | 0.84 | CHRM5 (0.43) | ACHECHRM5ADRA2CCACNA2D1CACNA1B | |
| SCHEMBL3436997 | 0.84 | NCF1 (0.52) | ACHECHRM5ADRA2CCACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023255-A1 | BIFUNCTIONAL DEGRADERS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND THERAPEUTIC USE THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2022266249-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| EP-3943086-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BioSplice Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-3448838-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BIOSPLICE THERAPEUTICS INC (US) | 2021-08-11 | — | — | EP | disclosed |
| US-20160366909-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160032038-A1 | POLYMERIC IONIC SALT CATALYSTS AND METHODS OF PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-02-04 | — | — | US | disclosed |
| US-9238845-B2 | Methods of producing sugars from biomass feedstocks | MIDORI USA, INC. (US) | 2016-01-19 | — | — | US | disclosed |
| US-20160007642-A1 | OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF | MIDORI USA, INC. (US) | 2016-01-14 | — | — | US | disclosed |
| US-20150202607-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS | Midori Renewables, Inc. (US) | 2015-07-23 | — | — | US | disclosed |
| WO-2014159558-A1 | POLYMERIC IONIC SALT CATALYSTS AND METHODS OF PRODUCING THEREOF | Midori Renewables, Inc. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140060522-A1 | METHODS OF PRODUCING SUGARS FROM BIOMASS FEEDSTOCKS | HERCULES CAPITAL, INC. | 2014-03-06 | — | — | US | disclosed |
| US-8507484-B2 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507484-B2 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20070213361-A1 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | KYOWA KIRIN CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213361-A1 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | KYOWA KIRIN CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160366909-A1 | OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF | FUT5, FUT6, OSTC | ACHE 3795/4885CHRM5 3655/4885ADRA2C 4113/4885 |
| US-20070213361-A1 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | MPO, MSR1, NR4A3 | ACHE 2154/4885CHRM5 822/4885ADRA2C 1301/4885 |
| US-20150202607-A1 | POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS | MGAM, CEL, SI | ACHE 504/4885CHRM5 3686/4885ADRA2C 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.