Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | COMT | P21964 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304470 | 0.75 | METAP2 (0.38) | METAP2ALDH1A1GAARAB9ALMNA | |
| SCHEMBL1828724 | 0.75 | CYP1A2 (0.37) | ALDH1A1CYP1A2HPGDKMT2AGAA | |
| SCHEMBL1828122 | 0.75 | SMN1; SMN2 (0.36) | METAP2TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL10476670 | 0.75 | BACE1 (0.47) | METAP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5748085 | 0.75 | GABRA1 (0.42) | METAP2KMT2ALMNA | |
| SCHEMBL4467203 | 0.75 | MCHR1 (0.51) | ALDH1A1CYP3A4KMT2ARAB9AMAPT | |
| SCHEMBL68795 | 0.74 | CCR1 (0.39) | TSHRMMP2CYP3A4HIF1AKDM4E | |
| SCHEMBL8487622 | 0.73 | ALDH1A1 (0.47) | TSHRALOX12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4810494 | 0.72 | ALDH1A1 (0.43) | METAP2TSHRMETAP1ALOX12ALDH1A1 | |
| SCHEMBL669119 | 0.72 | POLB (0.38) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689944-A | Quinoline tryptamine heterozygote and application thereof in preparation of medicine for treating Alzheimer disease | 中山大学 | 2020-09-22 | — | — | CN | claimed |
| CN-107880153-B | 6-carboxyl chitosan aromatic quaternary ammonium salt derivative and preparation and application thereof | 中国科学院海洋研究所 | 2020-05-05 | — | — | CN | claimed |
| US-9732227-B2 | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORPORATION (US) | 2017-08-15 | — | — | US | claimed |
| US-20160075880-A1 | Modified Colorants and Inkjet Ink Compositions Comprising Modified Colorants | CABOT CORPORATION | 2016-03-17 | — | — | US | claimed |
| US-20140100354-A1 | PEPTOID COMPOSITIONS AND METHODS OF USING THE SAME | NEW YORK UNIVERSITY | 2014-04-10 | — | — | US | claimed |
| US-8455643-B2 | 8-hydroxyquinoline-based white-light-emitting organic electroluminescent material | TAIYUAN UNIVERSITY OF TECHNOLOGY (CN) | 2013-06-04 | — | — | US | claimed |
| US-20110263856-A1 | 8-HYDROXYQUINOLINE-BASED WHITE-LIGHT-EMITTING ORGANIC ELECTROLUMINESCENT MATERIAL | TAIYUAN UNIVERSITY OF TECHNOLOGY (CN) | 2011-10-27 | — | — | US | claimed |
| US-20100292266-A1 | Oxazolyl Piperidine Modulators of Fatty Acid Amide Hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-18 | — | — | US | claimed |
| US-7732461-B2 | (4S)-4-({4-[(2,3-Dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)amino]-1-piperidinyl}methyl)-3-fluoro-4-hydroxy-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one, used in the treatment of bacterial infections caused by a wide range of organisms including both gramnegative and grampositive bacteria | GLAXO GROUP LIMITED (GB) | 2010-06-08 | — | — | US | claimed |
| US-20090318667-A1 | Peptoid compositions and methods of using the same | NEW YORK UNIVERSITY | 2009-12-24 | — | — | US | claimed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | claimed |
| EP-0991645-A1 | BIS-INDOLE DERIVATIVES HAVING ANTIMETASTATIC ACTIVITY, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | claimed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | claimed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | claimed |
| WO-1999000381-A1 | BIS-INDOLE DERIVATIVES HAVING ANTIMETASTATIC ACTIVITY, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 1999-01-07 | — | — | WO | claimed |
| EP-0887348-A1 | Bis-Indole derivatives having antimetastatic activity, a process for their preparation and pharmaceutical compositions containing them | Boehringer Mannheim Italia S.p.A. (IT) | 1998-12-30 | — | — | EP | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| US-4212802-A | GRAY SHADES | SANDOZ LTD. (CH) | 1980-07-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140100354-A1 | PEPTOID COMPOSITIONS AND METHODS OF USING THE SAME | PEPD, NGLY1, ANPEP | METAP2 364/4885TSHR 3167/4885MMP2 746/4885 |
| US-20100292266-A1 | Oxazolyl Piperidine Modulators of Fatty Acid Amide Hydrolase | FAAH, FAAH2, APEH | METAP2 1059/4885TSHR 2385/4885MMP2 1104/4885 |
| US-20090318667-A1 | Peptoid compositions and methods of using the same | PEPD, NGLY1, ANPEP | METAP2 364/4885TSHR 3167/4885MMP2 746/4885 |
| US-20110263856-A1 | 8-HYDROXYQUINOLINE-BASED WHITE-LIGHT-EMITTING ORGANIC ELECTROLUMINESCENT MATERIAL | OCIAD1, OCIAD2, EHD1 | METAP2 4781/4885TSHR 4758/4885MMP2 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.