Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27724084 | 0.81 | KEAP1 (0.42) | TSHRHTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL8641015 | 0.78 | AKR1B1 (0.50) | AKR1B1PTGS1MAPTMMP2CYP1A2 | |
| SCHEMBL1450954 | 0.78 | AKR1B1 (0.50) | AKR1B1GAAABCC4LMNATSHR | |
| SCHEMBL28757846 | 0.77 | CXCL8 (0.41) | AKR1B1GAAABCC4LMNATSHR | |
| SCHEMBL6762279 | 0.75 | — | — | |
| SCHEMBL28030866 | 0.75 | MTNR1A (0.35) | SMN1; SMN2KDM4E | |
| SCHEMBL21054410 | 0.74 | PTGS1 (0.45) | AKR1B1GAAABCC4LMNATSHR | |
| SCHEMBL27818826 | 0.73 | — | — | |
| SCHEMBL7969805 | 0.72 | AKR1B1 (0.47) | AKR1B1PTGS1MAPTMMP2CYP1A2 | |
| SCHEMBL6723732 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | claimed |
| EP-2907512-A1 | Inhibitors of MMP-12 as antiviral Agents | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-08-19 | — | — | EP | claimed |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) | 2012-12-06 | — | — | US | claimed |
| EP-2470514-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2012-07-04 | — | — | EP | claimed |
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | claimed |
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |
| EP-2907512-A1 | Inhibitors of MMP-12 as antiviral Agents | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-08-19 | — | — | EP | disclosed |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENE ALT (FR) | 2012-12-06 | — | — | US | disclosed |
| EP-2470514-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2012-07-04 | — | — | EP | disclosed |
| US-8129557-B2 | Phosphonic acid diester derivative and method for producing thereof | Nagai, Kazuhiro (JP) | 2012-03-06 | — | — | US | disclosed |
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | disclosed |
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | HIRATAKE, GOU (JP) | 2009-06-25 | — | — | US | disclosed |
| CN-101336246-A | Phosphonic acid diester derivative and method for producing same | HIRATAKE JUN (JP) | 2008-12-31 | — | — | CN | disclosed |
| WO-2008137446-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY DISEASE | TRUSTEES OF BOSTON UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
| EP-0922704-B1 | PROCESS FOR PREPARING 2-(10,11-DIHYDRO-10-OXODIBENZO b,f]THIEPIN-2-YL)PROPIONIC ACID AND INTERMEDIATES THEREFOR | NIPPON CHEMIPHAR CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| CN-1095840-C | Process for preparing 2- (10, 11-dihydro-10-oxodibenzo [ b, f ] thiepin-2-yl) propionic acid and intermediate compounds thereof | NIPPON CHEMIPHAR CO (JP) | 2002-12-11 | — | — | CN | disclosed |
| EP-0922704-A4 | PROCESS FOR PREPARING 2-(10,11-DIHYDRO-10-OXODIBENZO b,f]THIEPIN-2-YL)PROPIONIC ACID AND INTERMEDIATES THEREFOR | NIPPON CHEMIPHAR CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| CN-1234030-A | Process for preparing 2-(10,11-dihydro-10-oxodibenzo [b,f] thiepin-2-yl) propionic acid and intermediates therefor | NIPPON CHEMIPHAR CO (JP) | 1999-11-03 | — | — | CN | disclosed |
| WO-1998007717-A1 | PROCESS FOR PREPARING 2-(10,11-DIHYDRO-10-OXODIBENZO[b,f]THIEPIN-2-YL)PROPIONIC ACID AND INTERMEDIATES THEREFOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | PPA1, G6PD, PHOSPHO1 | AKR1B1 353/4885GAA 1922/4885ABCC4 4275/4885 |
| US-20120309674-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | MMP3, MMP11, TIMP3 | AKR1B1 2380/4885GAA 172/4885ABCC4 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.