Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231784 | 0.83 | KDM4E (0.67) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL14424521 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL7124523 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL13236780 | 0.81 | NOD2 (0.68) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL30228412 | 0.81 | KCNA3 (0.62) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL5691199 | 0.81 | KCNA3 (0.62) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL31089772 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDRAB9AKMT2AMAOA | |
| SCHEMBL14424525 | 0.79 | MAOA (0.63) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL5396788 | 0.79 | KCNA3 (0.62) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL14424527 | 0.79 | KDM4E (0.73) | ALDH1A1KDM4EHPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259265-B2 | Coumarin compounds and method for preparing and using the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2007-08-21 | — | — | US | disclosed |