SCHEMBL14428484

SCHEMBL14428484

O=Cc1ccc(Oc2ccccc2)cc1NC(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HTT P42858 4/20 0.49
POLB P06746 1/20 0.49
HDAC8 Q9BY41 1/20 0.48
MAPT P10636 1/20 0.48
CHRNB2 P17787 2/20 0.48
CHRNB4 P30926 2/20 0.48
CHRNA3 P32297 2/20 0.48
CHRNA4 P43681 2/20 0.48
ALDH1A1 P00352 3/20 0.46
STK39 Q9UEW8 2/20 0.46
TP53 P04637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PNLIP P16233 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272800 0.86 HTT (0.52) GAAKDM4EHTTPOLBMAPT
SCHEMBL14428222 0.85 PNLIP (0.61) GAAKDM4EHTTMAPTALDH1A1
SCHEMBL14428460 0.84 L3MBTL1 (0.60) GAASTK39L3MBTL1PNLIP
SCHEMBL14429560 0.84 HTT (0.55) GAAKDM4EHTTMAPTCHRNB2
SCHEMBL14428253 0.81 FABP1 (0.56) POLBHDAC8ALDH1A1
SCHEMBL13890889 0.78 MTNR1A (0.49) GAAHDAC8ALDH1A1
SCHEMBL14428218 0.77 HDAC2 (0.54) HDAC8
SCHEMBL15428172 0.75 PDK1 (0.44) GAAKDM4EHDAC8MAPTALDH1A1
SCHEMBL14428477 0.74 P2RX1 (0.46) KDM4EMAPT
SCHEMBL14428494 0.74 PGR (0.66) HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed