SCHEMBL14428222

SCHEMBL14428222

O=Cc1ccc(Oc2ccccc2)cc1NC(=O)c1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 8/20 0.61
STK39 Q9UEW8 2/20 0.49
NPC1 O15118 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LMNA P02545 3/20 0.49
HTT P42858 3/20 0.49
TP53 P04637 2/20 0.49
GAA P10253 1/20 0.49
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KCNMA1 Q12791 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14428460 0.86 L3MBTL1 (0.60) PNLIPSTK39NPC1MEN1KMT2A
SCHEMBL2274195 0.86 PNLIP (0.66) PNLIPSTK39NPC1MEN1KMT2A
SCHEMBL14428484 0.85 GAA (0.49) PNLIPSTK39MAPTHTTTP53
SCHEMBL14290073 0.81 LMNA (0.57) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL13890889 0.80 MTNR1A (0.49) NPC1KMT2ARAB9ASMN1; SMN2LMNA
SCHEMBL14428253 0.78 FABP1 (0.56) NPC1MEN1KMT2ARAB9AALDH1A1
SCHEMBL15428172 0.77 PDK1 (0.44) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL14428477 0.76 P2RX1 (0.46) MAPTKDM4E
SCHEMBL14428218 0.76 HDAC2 (0.54)
SCHEMBL14428494 0.76 PGR (0.66) NPC1MEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed