Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439826 | 0.87 | TSHR (0.39) | TSHRALDH1A1CAPN1VCPPDE9A | |
| SCHEMBL6974600 | 0.81 | TSHR (0.33) | TSHRALDH1A1CAPN1VCPPDE9A | |
| SCHEMBL5852619 | 0.81 | TACR1 (0.34) | TSHRCAPN1VCPPDE9APDE1A | |
| SCHEMBL4893143 | 0.81 | TSHR (0.43) | TSHRALDH1A1CAPN1VCPLMNA | |
| SCHEMBL6964698 | 0.79 | LMNA (0.36) | LMNAPOLBPDE9APDE1APDE1B | |
| SCHEMBL5029294 | 0.79 | DHFR (0.41) | ALDH1A1LMNAKMT2AHCAR2NPC1 | |
| SCHEMBL6971891 | 0.71 | ALDH1A1 (0.37) | ALDH1A1CAPN1DHODHHCAR2 | |
| SCHEMBL6973717 | 0.70 | LMNA (0.35) | ALDH1A1LMNAPOLBKMT2ADHODH | |
| SCHEMBL4903158 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1CAPN1VCPPDE9A | |
| SCHEMBL6963019 | 0.69 | APP (0.40) | CA1CA2HCAR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |