Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181140 | 0.81 | NPC1 (0.41) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL9906396 | 0.80 | ALDH1A1 (0.57) | NPC1RAB9ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL10181733 | 0.80 | NPC1 (0.46) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL10181070 | 0.79 | ENPP2 (0.45) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL10180558 | 0.79 | PSIP1 (0.50) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL12807500 | 0.77 | LMNA (0.50) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL25111544 | 0.77 | CA2 (0.42) | LMNASMN1; SMN2MAPTALDH1A1DRD3 | |
| SCHEMBL4733508 | 0.77 | LMNA (0.45) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL22518681 | 0.77 | NPC1 (0.43) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL344370 | 0.77 | NPC1 (0.43) | NPC1RAB9ALMNAMAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | SCHERING CORPORATION | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | CNR1, CNR2, GPR119 | NPC1 237/4885RAB9A 1082/4885LMNA 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.