Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316750 | 0.86 | KIF11 (0.48) | KIF11GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL5316958 | 0.84 | VCP (0.52) | KIF11GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL5318196 | 0.84 | KDR (0.52) | KIF11GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL5341998 | 0.81 | PKM (0.47) | KIF11GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL5338297 | 0.80 | SYK (0.54) | KIF11GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL5334965 | 0.80 | VCP (0.57) | KIF11GABRG2GABRB3GABRA5CYP11B1 | |
| SCHEMBL5319534 | 0.77 | VCP (0.52) | SYKMEN1ALDH1A1GAAMAPT | |
| SCHEMBL5318237 | 0.77 | SMO (0.63) | TNIKKDRIMPDH2SMOMEN1 | |
| SCHEMBL5339461 | 0.76 | KDR (0.52) | SYKROCK1KDRIMPDH2ALDH1A1 | |
| SCHEMBL5319083 | 0.75 | GRIA1 (0.43) | SYKROCK1KDRIMPDH2SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |