Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12364193 | 0.91 | MEP1B (0.36) | ALDH1A1KDM4EHSD17B10SCN10ANPC1 | |
| SCHEMBL1224599 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10SCN10AHTR1A | |
| SCHEMBL1224460 | 0.88 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10SCN10ANPC1 | |
| SCHEMBL678359 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10SCN10AHTR1A | |
| SCHEMBL29443526 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10SCN10AHTR1A | |
| SCHEMBL14478771 | 0.81 | LMNA (0.34) | — | |
| SCHEMBL679753 | 0.80 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10SCN10APKM | |
| SCHEMBL679154 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10SCN10AHTR1A | |
| SCHEMBL29769728 | 0.80 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10SCN10APKM | |
| Potassium SCHEMBL679156 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10SCN10AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199943-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-20130237422-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130005577-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237422-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DDT, DDC, HDHD5 | ALDH1A1 839/4885KDM4E 567/4885HSD17B10 2745/4885 |
| US-20130005577-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DDT, DDC, HDHD5 | ALDH1A1 839/4885KDM4E 567/4885HSD17B10 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.