Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537959 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL15339364 | 0.82 | TSHR (0.48) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL8808020 | 0.82 | ADRA2A (0.48) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL761659 | 0.82 | TSHR (0.48) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL9242348 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL24117207 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL28292418 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL3686642 | 0.74 | TSHR (0.59) | ALDH1A1HTTTSHRCA9KMT2A | |
| SCHEMBL10620953 | 0.74 | LTA4H (0.57) | ALDH1A1HSD17B10HTTTSHRCYP3A4 | |
| SCHEMBL13107871 | 0.74 | MAPT (0.58) | ALDH1A1HTTTDP1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070134729-A1 | Novel antibacterial agents | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070134729-A1 | Novel antibacterial agents | ENGASE, PGLS, PEPD | ALDH1A1 2244/4885HSD17B10 963/4885HTT 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.