Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 13/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14538755 | 0.90 | FAAH (0.47) | LTA4HHRH3HTT | |
| SCHEMBL4608914 | 0.86 | SLC6A3 (0.47) | HRH3HTT | |
| SCHEMBL4609211 | 0.83 | LTA4H (0.42) | LTA4HHTT | |
| SCHEMBL15908896 | 0.82 | NPY1R (0.51) | HTT | |
| SCHEMBL4608156 | 0.81 | SLC6A3 (0.46) | HRH3HTT | |
| SCHEMBL4610443 | 0.81 | HRH3 (0.40) | LTA4HHRH3HTT | |
| SCHEMBL4608505 | 0.80 | HRH3 (0.53) | HRH3 | |
| SCHEMBL4607915 | 0.78 | ACHE (0.45) | HRH3 | |
| SCHEMBL4608119 | 0.77 | SLC6A3 (0.39) | HTT | |
| SCHEMBL4653088 | 0.76 | NPY1R (0.47) | HRH3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061741-A2 | MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | disclosed |