Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334481 | 0.89 | HRH1 (0.50) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL5536476 | 0.88 | HRH1 (0.53) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL5544614 | 0.86 | HRH1 (0.56) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL5252524 | 0.86 | HRH1 (0.56) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL7770374 | 0.81 | HRH1 (0.50) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL444168 | 0.81 | SMN1; SMN2 (0.49) | HRH1LMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9411278 | 0.79 | CA12 (0.47) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL8741255 | 0.79 | CA12 (0.47) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL7449287 | 0.78 | HRH1 (0.59) | HRH1CA12CA1CA2CA9 | |
| SCHEMBL1263459 | 0.76 | NAAA (0.35) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | claimed |
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | disclosed |
| US-11066430-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| EP-3434713-B1 | METHODS OF PREPARING AND PURIFYING POLYALKYLENE GLYCOL DERIVATIVES | SHINETSU CHEMICAL CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10836861-B2 | Methods of preparing and purifying polyalkylene glycol derivative | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-10550136-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-02-04 | — | — | US | disclosed |
| US-10472377-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20190322688-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | SHINETSU CHEMICAL CO (JP) | 2019-10-24 | — | — | US | disclosed |
| US-20190315777-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | SHINETSU CHEMICAL CO (JP) | 2019-10-17 | — | — | US | disclosed |
| US-10377775-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | disclosed |
| WO-1993018003-A1 | SUBSTITUED PIPECOLINIC ACID DERIVATIVES AS HIV PROTEASE INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-16 | — | — | WO | disclosed |
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
| EP-0488301-A1 | New benzopyran compounds with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-03 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| EP-0309841-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0292800-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377775-B2 | Method for producing polyalkylene glycol derivative having amino group at end | KCNMA1, KCNMB1, KCNMB4 | HRH1 1456/4885CA12 2278/4885CA1 1131/4885 |
| US-11066430-B2 | Method for producing polyalkylene glycol derivative having amino group at end | RAD1, AP3B1, RER1 | HRH1 1738/4885CA12 1807/4885CA1 977/4885 |
| US-10472377-B2 | Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator | ADH1A, ADH1C, AP3M1 | HRH1 793/4885CA12 1927/4885CA1 782/4885 |
| US-10550136-B2 | Method for producing polyalkylene glycol derivative having amino group at end | RAD1, AP3B1, RER1 | HRH1 1728/4885CA12 1767/4885CA1 932/4885 |
| US-20190315777-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | KCNMA1, KCNMB1, KCNMB4 | HRH1 1456/4885CA12 2239/4885CA1 1092/4885 |
| US-20190322688-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | RAD1, AP3B1, RER1 | HRH1 1738/4885CA12 1807/4885CA1 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.