Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645032 | 0.85 | DRD2 (0.43) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8255716 | 0.83 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1DRD2 | |
| SCHEMBL29358366 | 0.82 | CHRNB2 (0.44) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8055435 | 0.80 | EPHX1 (0.43) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8038051 | 0.80 | EPHX1 (0.43) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL11240147 | 0.80 | OPRM1 (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL8050286 | 0.79 | MTNR1A (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL15934293 | 0.79 | MTNR1A (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL21661030 | 0.79 | MTNR1A (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 | |
| SCHEMBL12506716 | 0.78 | FAP (0.44) | CHRNB2CHRNA7CHRNA4CHRNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | claimed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |