Sugi Predict

Sugi Predict / Compounds / SCHEMBL145744

SCHEMBL145744

SCHEMBL145744

[CH2]C(CCCC)c1cccs1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GLA P06280 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ CTSK P43235 1/20 0.35
▸ HDAC3 O15379 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ HSPA5 P11021 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC11 Q96DB2 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ CES2 O00748 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ KEAP1 Q14145 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8653457 0.95 GLA (0.35) GLATSHRHTTL3MBTL1CTSK
SCHEMBL7467588 0.93 HDAC1 (0.37) GLATSHRHTTL3MBTL1HDAC3
SCHEMBL94449 0.80 — —
SCHEMBL7284168 0.79 NPC1 (0.50) GLATSHRHTTL3MBTL1CTSK
SCHEMBL7276887 0.79 NPC1 (0.50) GLATSHRHTTL3MBTL1CTSK
SCHEMBL175346 0.79 GLA (0.40) GLATSHRHTTL3MBTL1CTSK
SCHEMBL7269210 0.79 NPC1 (0.50) GLATSHRHTTL3MBTL1CTSK
SCHEMBL23695275 0.78 CA2 (0.43) GLATSHRHTTL3MBTL1CTSK
SCHEMBL2887376 0.78 KDM4E (0.44) GLATSHRHTTL3MBTL1CTSK
SCHEMBL16334692 0.78 GLA (0.39) GLATSHRHTTL3MBTL1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 — — EP disclosed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 — — EP disclosed
US-20150291830-A1 APPARATUS AND METHODS FOR PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION OF POLYMER COATINGS LIQUIPEL IP LLC (US) 2015-10-15 — — US disclosed
CN-103209717-B Lubricious coatings for medical devices BIOINTERACTIONS LTD 2015-04-08 — — CN disclosed
US-8852640-B2 Micelles for delivery of nitric oxide ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2014-10-07 — — US disclosed
US-20140141674-A1 APPARATUS AND METHODS FOR PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION OF DIELECTRIC/POLYMER COATINGS LIQUIPEL IP LLC 2014-05-22 — — US disclosed
US-20140141221-A1 APPARATUS AND METHODS FOR PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION OF POLYMER COATINGS Liquipel, LLC (US) 2014-05-22 — — US disclosed
WO-2014078488-A1 APPARATUS AND METHODS FOR PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION OF POLYMER COATINGS LIQUIPEL IP LLC (US) 2014-05-22 — — WO disclosed
WO-2014078497-A1 APPARATUS AND METHODS FOR PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION OF DIELECTRIC/POLYMER COATINGS LIQUIPEL IP LLC (US) 2014-05-22 — — WO disclosed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 — — US disclosed
EP-1473599-A1 Organophotoreceptors with azine-based compounds Samsung Electronics Co., Ltd. (KR) 2004-11-03 — — EP disclosed
EP-1471391-A1 Polymeric charge transport compositions Samsung Electronics Co., Ltd. (KR) 2004-10-27 — — EP disclosed
CN-1540448-A Polymeric charge transport compsns. ���ǵ�����ʽ���� 2004-10-27 — — CN disclosed
EP-1465020-A2 Organophotoreceptor with a charge transport compound having an epoxy group Samsung Electronics Co., Ltd. (KR) 2004-10-06 — — EP disclosed
US-20040191655-A1 Polymeric charge transport compositions S-PRINTING SOLUTION CO., LTD. (KR) 2004-09-30 — — US disclosed
US-20040170910-A1 Organophotoreceptor with a charge transport material having two hydrazone groups S-PRINTING SOLUTION CO., LTD. (KR) 2004-09-02 — — US disclosed
US-20040170909-A1 Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups S-PRINTING SOLUTION CO., LTD. (KR) 2004-09-02 — — US disclosed
EP-1452924-A1 Organophotoreceptor with charge transport material having two hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-09-01 — — EP disclosed
EP-1452925-A1 Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups Samsung Electronics Co., Ltd. (KR) 2004-09-01 — — EP disclosed
US-20040161685-A1 Organophotoreceptor with a charge transport compound having an epoxy group S-PRINTING SOLUTION CO., LTD. (KR) 2004-08-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170909-A1 Organophotoreceptor with a charge transport material having two (9-fluorenylidene) malononitrile groups SLC39A14, SLC37A4, SLC39A7 GLA 1829/4885TSHR 1629/4885HTT 2860/4885
US-20040170910-A1 Organophotoreceptor with a charge transport material having two hydrazone groups SLC16A7, SLC43A1, SLC16A8 GLA 3043/4885TSHR 753/4885HTT 1403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.