Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.77 |
| ▸ | DRD2 | P14416 | 6/20 | 0.76 |
| ▸ | DRD3 | P35462 | 6/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27959850 | 0.87 | IGF1R (1.00) | IGF1RDRD2DRD3SIGMAR1HTR1A | |
| SCHEMBL13532634 | 0.86 | DRD2 (1.00) | IGF1RDRD2DRD3SIGMAR1SLC6A2 | |
| SCHEMBL11968814 | 0.84 | IGF1R (0.55) | IGF1RDRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL1460235 | 0.80 | KMT2A (0.80) | IGF1RSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL10729822 | 0.79 | IGF1R (0.65) | IGF1RDRD2DRD3SIGMAR1HTR1A | |
| SCHEMBL10731883 | 0.79 | IGF1R (0.65) | IGF1RDRD2DRD3SIGMAR1HTR1A | |
| SCHEMBL11969601 | 0.79 | SLC6A2 (0.56) | IGF1RDRD2DRD3SIGMAR1SLC6A2 | |
| SCHEMBL1461231 | 0.78 | L3MBTL1 (0.58) | IGF1RDRD2DRD3SIGMAR1KDM4E | |
| SCHEMBL30874651 | 0.78 | IGF1R (0.64) | IGF1RHTR1ALMNASMN1; SMN2DRD4 | |
| SCHEMBL10587768 | 0.78 | IGF1R (0.64) | IGF1RDRD2DRD3SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
| EP-2475643-A1 | NOVEL ETHANE DIAMINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011026959-A1 | NOVEL ETHANE DIAMINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214798-A1 | Novel Ethanediamone Hepcidine Antagonists | HAMP, SLC40A1, FTH1 | IGF1R 2196/4885DRD2 1519/4885DRD3 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.