Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716477 | 1.00 | ALOX5 (0.58) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL19738196 | 0.90 | ALOX5 (0.50) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL27715815 | 0.90 | ALOX5 (0.49) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL19456746 | 0.89 | THRB (0.56) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL22195188 | 0.85 | THRB (0.49) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL19738396 | 0.84 | THRB (0.51) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL1592402 | 0.84 | MMP2 (0.51) | ALOX5THRBHCAR2 | |
| SCHEMBL31744993 | 0.83 | CA12 (0.64) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL1119161 | 0.83 | CA12 (0.64) | ALOX5CA12CA4CA6CA5A | |
| SCHEMBL19738374 | 0.83 | ALOX5 (0.44) | ALOX5CA12CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| US-11618823-B2 | High refractive index siloxane insert materials for embedded contact lenses | ALCON INC. (CH) | 2023-04-04 | — | — | US | claimed |
| EP-4121802-A1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | Alcon Inc. (CH) | 2023-01-25 | — | — | EP | claimed |
| EP-1080381-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD | ALCON LABORATORIES, INC. (US) | 2001-03-07 | — | — | EP | claimed |
| US-6187042-B1 | COMPRISING A SUBSTRATE AND A COATING FOR MAKING THE LENS MORE BIOCOMPATIBLE AND REDUCING THE RISK OF POSTERIOR CAPSULE OPACIFICATION, THE COATING IS BASED ON A POLYMER OF TWO HYDROPHOBIC ACRYLIC ESTERS CONTAINING A PHENYL GROUP | ALCON LABORATORIES, INC. | 2001-02-13 | — | — | US | claimed |
| EP-1071482-A1 | INTRAOCULAR LENS COATING COMPOSITIONS | Alcon Laboratories, Inc. (US) | 2001-01-31 | — | — | EP | claimed |
| EP-1002244-A1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-1999052570-A1 | INTRAOCULAR LENS COATING COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-1999053348-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| WO-1999052571-A1 | BICOMPOSITE INTRAOCULAR LENS AND METHOD FOR ITS PREPARATION | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| US-5891931-A | CONTAINING A CURABLE ACRYLATED RESIN POLYMER | ALCON LABORATORIES, INC. (US) | 1999-04-06 | — | — | US | claimed |
| WO-1999008136-A1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-02-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | ALOX5 2585/4885CA12 2034/4885CA4 2701/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | ALOX5 36/4885CA12 3619/4885CA4 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.