Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620482 | 0.88 | TDP1 (0.44) | HPGDMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL14620125 | 0.85 | MEN1 (0.47) | EPHX1HPGDMAPTMEN1KMT2A | |
| SCHEMBL14620126 | 0.85 | CA1 (0.45) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL14620480 | 0.85 | SMN1; SMN2 (0.44) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14620353 | 0.85 | MTNR1A (0.44) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8403295 | 0.77 | EPHX1 (0.47) | EPHX1HPGDMAPTMEN1KMT2A | |
| SCHEMBL14588757 | 0.77 | SMN1; SMN2 (0.44) | EPHX1HPGDMAPTMEN1KMT2A | |
| SCHEMBL14620311 | 0.72 | CTSD (0.49) | HPGDKMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL14620458 | 0.72 | SMN1; SMN2 (0.40) | EPHX1HPGDMAPTMEN1KMT2A | |
| SCHEMBL1531237 | 0.72 | ERCC5 (0.58) | HPGDMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |