Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620458 | 0.86 | SMN1; SMN2 (0.40) | CTSDNPC1HPGDLMNAKMT2A | |
| SCHEMBL14620353 | 0.81 | MTNR1A (0.44) | NPC1LMNAKMT2AGAARAB9A | |
| SCHEMBL14588761 | 0.79 | CTSD (0.47) | CTSDNPC1MAPK1HPGDLMNA | |
| SCHEMBL29138521 | 0.77 | MAPT (0.46) | CTSDNPC1MAPK1HPGDLMNA | |
| SCHEMBL14620126 | 0.75 | CA1 (0.45) | NPC1LMNARAB9AMTNR1AMTNR1B | |
| SCHEMBL14620480 | 0.75 | SMN1; SMN2 (0.44) | NPC1MAPK1KMT2AGAARAB9A | |
| SCHEMBL447573 | 0.75 | NPC1 (0.70) | CTSDNPC1HPGDLMNATP53 | |
| SCHEMBL14620482 | 0.75 | TDP1 (0.44) | NPC1HPGDLMNAKMT2AGAA | |
| SCHEMBL14620481 | 0.72 | PTGS2 (0.40) | NPC1HPGDLMNAKMT2AGAA | |
| SCHEMBL14620125 | 0.72 | MEN1 (0.47) | NPC1MAPK1HPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |