Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620482 | 0.88 | TDP1 (0.44) | LMNACES2CES1ALDH1A1PKM | |
| SCHEMBL14620125 | 0.85 | MEN1 (0.47) | LMNAL3MBTL1ALDH1A1MAPTNPC1 | |
| SCHEMBL14620480 | 0.85 | SMN1; SMN2 (0.44) | L3MBTL1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL14620481 | 0.85 | PTGS2 (0.40) | LMNACES2CES1L3MBTL1ALDH1A1 | |
| SCHEMBL14620353 | 0.85 | MTNR1A (0.44) | LMNAALDH1A1NPC1RAB9AMTNR1A | |
| SCHEMBL14247743 | 0.77 | CA1 (0.49) | CA1CA2CES2CES1PLK1 | |
| SCHEMBL14247744 | 0.77 | CA1 (0.49) | CA1CA2CES2CES1PLK1 | |
| SCHEMBL9125304 | 0.76 | CES2 (0.55) | CA1CA2CES2CES1PLK1 | |
| SCHEMBL9125300 | 0.76 | CES2 (0.55) | CA1CA2CES2CES1PLK1 | |
| SCHEMBL14620311 | 0.75 | CTSD (0.49) | LMNAL3MBTL1NPC1RAB9AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |