Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620482 | 0.88 | TDP1 (0.44) | MEN1KMT2AATMALDH1A1LMNA | |
| SCHEMBL14620481 | 0.85 | PTGS2 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL14620126 | 0.85 | CA1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL14620480 | 0.85 | SMN1; SMN2 (0.44) | MEN1KMT2AATML3MBTL1ALDH1A1 | |
| SCHEMBL14620353 | 0.85 | MTNR1A (0.44) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL14588756 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2ACYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL14620311 | 0.72 | CTSD (0.49) | KMT2AL3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL14620458 | 0.72 | SMN1; SMN2 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL11827259 | 0.72 | GSK3B (0.55) | MEN1KMT2ACYP1A2ATML3MBTL1 | |
| Water SCHEMBL27463157 | 0.69 | MAOB (0.54) | MEN1KMT2ACYP1A2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |